Autophagy in mammalian systems. Part B /

Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in unde...

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Bibliographic Details
Call Number:Libro Electrónico
Other Authors: Klionsky, Daniel J. (Editor)
Format: Electronic eBook
Language:Inglés
Published: San Diego, California ; London : Academic Press/Elsevier, �2009.
Series:Methods in enzymology ; volume 452.
Subjects:
Cellular control mechanisms.
Autophagic vacuoles.
Apoptosis.
Eukaryotic cells.
Biological assay.
Autophagy > physiology
Cells > metabolism
Apoptosis
Eukaryotic Cells
Mammals > metabolism
Microtubule-Associated Proteins > metabolism
Biological Assay
R�egulation cellulaire.
Apoptose.
Cellules eucaryotes.
Essais biologiques.
SCIENCE > Life Sciences > Biochemistry.
Biological assay
Autophagic vacuoles
Cellular control mechanisms
Eukaryotic cells
degradatie
degradation
katabolisme
catabolism
celfysiologie
cell physiology
Metabolic Processes
Metabole processen
Online Access:Texto completo
Texto completo
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Description
Summary:Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 in yeast. These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. In this volume, a robust slate of methods for conducting research are presented, establishing a consensus of appropriate criteria for monitoring autophagy. Along with Autophagy: Lower Eukaryotes, this volume marks the seminal collection of methods in the burgeoning field of autophagy
Item Description:Called Part B in continuation of Part A issued as volume 451 of Methods in enzymology under title: Autophagy : Lower eukaryotes and non-mammalian species, Part A.
Physical Description:1 online resource (xlix, 508 pages, 12 unnumbered pages of plates) : illustrations (some color)
Bibliography:Includes bibliographical references and indexes.
ISBN:9780080923253
0080923259
9780123745477
0123745470
ISSN:0076-6879 ;

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