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Real world drug discovery : a chemist's guide to biotech and pharmaceutical research /

Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, c...

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Bibliographic Details
Call Number:Libro Electrónico
Main Author: Rydzewski, Robert M.
Format: Electronic eBook
Language:Inglés
Published: Amsterdam ; Boston : Elsevier, 2008.
Edition:1st ed.
Subjects:
Online Access:Texto completo
Table of Contents:
  • 1 The Drug Discovery Business to Date
  • 2 The Drug Discovery Business to Come
  • 3 Industrial Considerations
  • 4 How Things Get Done: The Project Team
  • 5 Project Considerations
  • 6 Hit Generation
  • 7 Turning Hits into Drugs
  • 8 Initial Properties
  • 9 ADME and PK Properties
  • 10 Toxicity-Related Properties
  • 11 A Career in Drug Discovery.
  • The drug discovery business to date
  • The drug discovery business to come
  • Industrial considerations
  • how things get done : the project team
  • Project considerations
  • Hit generation
  • Turning hits into drugs
  • Initial properties
  • ADME and PK properties
  • Toxicity related properties
  • A career in drug discovery research.