RNA turnover in eukaryotes : Nucleases, pathways and analysis of mRNA decay /

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maquat, Lynne (Editor ), Kiledjian, Megerditch (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, California ; London : Academic Press/Elsevier, �2008.
Colección:Methods in enzymology ; v. 448.
Temas:
Messenger RNA.
Genetic regulation.
Eukaryotic cells.
Nucleases.
RNA Precursors
RNA Stability > physiology
Gene Expression Regulation
Eukaryotic Cells
Eukaryotic Cells > metabolism
mRNA Cleavage and Polyadenylation Factors
RNA, Messenger > metabolism
R�egulation g�en�etique.
Cellules eucaryotes.
Nucl�eases.
SCIENCE > Life Sciences > Molecular Biology.
Eukaryotic cells
Genetic regulation
Messenger RNA
Nucleases
rna
metabolisme
metabolism
degradatie
degradation
Metabolic Processes
Metabole processen
Laboratory Manual
Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Acceso en línea:Texto completo
Texto completo
Texto completo
Descripción
Sumario:Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. The control of biological processes, such as cellular growth and differentiation, is dependent on how the genetic material within a cell is expressed. The cellular physiology of mRNA-including mRNA processing, transport, localization, and turnover-is central to the process of gene expression. Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway. Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover which are central to the process of gene expression. Offers step-by-step lab instructions including necessary equipment and reagents.
Descripción Física:1 online resource (xlviii, 607 pages, 5 unnumbered pages of plates) : illustrations (some color)
Bibliografía:Includes bibliographical references and indexes.
ISBN:9780080922072
0080922074
0123743788
9780123743787
1282287311
9781282287310
ISSN:0076-6879 ;

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