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Progress in medicinal chemistry. 3 /
PROGRESS IN MEDICINAL CHEMISTRY 3.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Butterworths,
1963.
|
| Colección: | Progress in medicinal chemistry ;
3 |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Progress in Medicinal Chemistry, Volume 3; Copyright Page; Contents; Preface; CHAPTER 1. SOME CHEMICAL ASPECTS OF NEUROMUSCULAR BLOCK; Introduction; Essential chemical requirements for motor end-plate block; The structure and environment of the onium group; Bis-onium compounds; Tris-onium compounds; Conclusions; CHAPTER 2. THE CHEMOTHERAPY OF TRYPANOSOMIASIS; Introduction; The causative organisms; Testing drugs for trypanocidal properties; Human trypanosomiasis in Africa; Trypanocides for human use; Veterinary trypanosomiasis in Africa; Trypanocides for veterinary use
- CHAPTER 3. ANTITUSSIVE DRUGSIntroduction; Pathophysiology of cough; Pharmacological approach to cough; Evaluation of antitussive drugs; Therapy of cough; Retrospect and prospects; CHAPTER 4. THE CHEMISTRY AND PHARMACOLOGY OF THE RAUWOLFIA ALKALOJDS; Introduction; Rauwolfia species and alkaloids isolated; Alkaloids with the yohimbine skeleton; The reserpine-type alkaloids; Ring E oxygen heterocycles; The ajmaline group; Unidentified alkaloids; CHAPTER 5. STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING; Introduction; Screening test designs; Direct assays; Quantal assays
- Quantitative assaysInteractions between drugs; 'The final choice'; CHAPTER 6. ANTICONVULSANT DRUGS; Introduction; Methods of testing anticonvulsants; Mode of action of anticonvulsants; Metabolism of anticonvulsants; Anticonvulsant drug therapy; Structure-activity relationships; Conclusion; CHAPTER 7. LOCAL ANAESTHE TICS; Introduction; Chemistry, lines of development and types of local anaesthetics; The relationship between structure and local anaesthetic activity; Mode of action of local anaesthetics; Screening and evaluation; Other pharmacological actions of local anaesthetics
- Toxicology arid toleranceThe relationship between systemic and local toxicity and anaesthetic activity; Metabolism; Local anaesthetics in clinical use; Aminoacylamides; Aminoalkyl esters of benzoic acid; Miscellaneous types of agents; Long-acting local anaeathetics ('depot preparations'); Index