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Advances in immunology. Volume 38 /

ADVANCES IN IMMUNOLOGY VOLUME 38.

Bibliographic Details
Call Number:Libro Electrónico
Other Authors: Dixon, Frank J. (Frank James), 1920-2008
Format: Electronic eBook
Language:Inglés
Published: Orlando ; San Diego ; London : Academic Press, 1986.
Series:Advances in immunology.
Subjects:
Online Access:Texto completo
Table of Contents:
  • Front Cover; Advances in Immunology, Volume 38; Copyright Page; Contents; Contributors; Chapter 1. The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells; I. Introduction; II. Identification and Properties of T Cell Receptor Proteins; III. Properties of cDNA and Genomic Clones Encoding T Cell Receptor Proteins; IV. Other Receptor-Like Genes in T Cells; V. Rearrangement and Expression of T Cell Receptor Genes in the Thymus; VI. Expression of Receptor Genes and Proteins on Peripheral T Cells; VII. V Region Repertoire and Variability.
  • VIII. Chromosomal Mapping of T Cell Receptor GenesIX. Allelic Exclusion of T Cell Receptor Genes; X. Association of the Receptor and T3; XI. Is the Receptor Responsible for Specific Binding to Both Antigen and MHC by T Cells?; XII. Interactions of T Cells with Their Targets; XIII. Concluding Remarks; References; Chapter 2. Immune Response (Ir) Genes of the Murine Major Histocompatibility Complex; I. Introduction; II. Early Observations; III. Cellular Sites of Expression of Ir Genes; IV. Parallels between MHC Restriction and Ir Gene Control; V. Ia Molecules Are the Ir Gene Products.
  • VI. Theories of Ir Gene FunctionVII. Ir Gene Control of T Cell-T Cell Interactions; VIII. Ir Gene Control of Cytotoxic T Cell Responses; IX. Conclusion; References; Chapter 3. The Molecular Genetics of Components of Complement; I. Introduction; II. C2 and Factor B; III. C4; IV. Clq; V. C3; VI. C5; VII. C9; VIII. C4b-Binding Protein (C4bp); IX. Summary; References; Chapter 4. Molecular Genetics of Human B Cell Neoplasia; I. Introduction; II. Chromosomal Translocations in B Cell Neoplasia; III. Translocation of the c-myc Oncogene in Burkitt Lymphomas with the t(8; 14) Chromosome Translocation.
  • IV. Deregulation of the Translocated c-myc oncogene in Burkitt LymphomaV. Molecular Genetics of the Variant Chromosome Translocations in Burkitt Lymphoma; VI. Mechanisms of c-myc Activation; VII. Molecular Genetics of the t(11; 14) Chromosome Translocation; VIII. Molecular Genetics of the (14; 18) Chromosome Translocation'; IX. Conclusions; References; Chapter 5. Human Lymphocyte Hybridomas and Monoclonal Antibodies; I. Introduction; II. Production of Monoclonal Antibodies by Epstein-ssssBarr Virus-Transformed B Cells; III. Cell Lines for B Lymphocyte Hybridization.
  • IV. Preparation of Donor Lymphocytes fror FusionV. Cell Fusion; VI. Human-Murine Hybridomas; VII. Human
  • Human Hybridomos; VIII. Human x Human -Mouse Heterohybridomas; IX. Characterization of Human Monoclonal Antibodies; X. Propagation of Human- Mouse and Human- Human Hybridomas in Vivo; XI. Genetically Engineered Antibodies; XII. Concluding Remarks; References; Chapter 6. Maternally Transmitted Antigen; I. Introduction; II. Nomenclature; III. Maternal Inheritance of Mta Polymorphisms; IV. Mta Shares Important Functional Properties with Class I Major Histocompatibility Antigens.