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Advances in pharmacology. Volume 22 /

ADVANCES IN PHARMACOLOGY VOL 22.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: August, J. Thomas, Anders, M. W. (Marion Walter), 1936-, Murad, Ferid
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press : Harcourt Brace Jovanovich, �1991.
Colección:Advances in pharmacology ; v. 22
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Advances in pharmacology.  |n Volume 22 /  |c edited by J. Thomas August, M.W. Anders, Ferid Murad. 
260 |a San Diego :  |b Academic Press :  |b Harcourt Brace Jovanovich,  |c �1991. 
300 |a 1 online resource (x, 374 pages) :  |b illustrations. 
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490 0 |a Advances in pharmacology ;  |v v. 22 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Cover; Contents; Contributors; Chapter 1. Acyclovir: Mechanism of Antiviral Action and Potentiation by Ri bonucleotide Reductase Inhibitors; I. Introduction; II. Acyclovir Transport; III. Metabolic Activation of Acyclovir; IV. Mechanism of Antiviral Action; V. Potentiation of the Antiviral Action of Acyclovir; VI. Resistance and Hypersensitivity to Acyclovir; VII. Conclusions; References; Chapter 2. Rational Approaches to Osteoporosis Therapy; I. Introduction; II. Age-Related Changes in Bone Mass; III. Mechanisms of Bone Mass Regulation; IV. Osteoporosis; V. Experimental Approaches. 
505 8 |a VI. Nonpharmacological ConsiderationsVII. Conclusions; References; Chapter 3. Molecular Asymmetry and Its Pharmacological Consequences; I. Introduction; II. Pharmacokinetic Consequences of Chirality; III. Chirality and Polymorphic Drug Disposition; IV. Pharmacodynamic Consequences of Chirality; V. Enantiomer-Enantiomer Interactions; VI. Enantioselective Drug-Enantiomer Interactions; VII. Enantiomeric Impurity and Potential Problems; VIII. Enantiomers as Biochemical Probes; IX. Therapeutic and Regulatory Considerations; X. Therapeutic Drug Monitoring; XI. Conclusions; References. 
505 8 |a Chapter 4. Blood-Brain Barrier: Transport Studies in Isolated Brain Capillaries and in Cultured Brain Endothelial CellsI. Introduction; II. Establishment and Characterization of an in Vitro Blood-Brain Barrier Model; III. In Vitro Transport Studies; IV. In Vitro Studies on Regulation of Blood-Brain Barrier Transport; V. Summary; References; Chapter 5. Protein Kinase Inhibitors: Probes for the Functions of Protein Phosphorylation; I. Introduction; II. Inhibitors of Protein Serine/Threonine Kinases; III. Inhibitors of Protein Tyrosine Kinases; IV. Concluding Remarks; References. 
505 8 |a Chapter 6. Renin InhibitorsI. Introduction; II. Physical and Functional Properties of Renin; III. Biochemical Evaluation and Specificity of Renin Inhibitors; IV. Design and Structure of Renin Inhibitors; V. Pharmacology of Renin Inhibitors; VI. Conclusion; References; Chapter 7. The Capacitative Model for Receptor-Activated Calcium Entry; I. Introduction; II. Epithelial Cells: Models for Studying Receptor-Activated Ca2+ Signaling; III. Mechanisms of Ca2+ Entry; IV. Conclusions; References; Chapter 8. Calcium Channel Antagonists in the Prevention of Neurotoxicity; I. Introduction. 
505 8 |a II. Potential Problems in Interpreting the Effectiveness of Calcium Channel Antagonists in Preventing NeurotoxicityIII. Types of Neurotoxicity Attenuated by Calcium Channel Antagonists; IV. The Hypothesis of Calcium-Associated Neuronal Damage; V. Potential Contribution of T, N, L, and P Types of Calcium Channels to Neurotoxicity; VI. Types of Voltage-Dependent Calcium Channel Antagonists; VII. In Vitro Models of Neurotoxicity and Effects of Calcium Channel Antagonists; VIII. In Vivo Animal Models of Ischemia and Effects of Calcium Channel Antagonists. 
520 |a ADVANCES IN PHARMACOLOGY VOL 22. 
650 0 |a Pharmacology. 
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700 1 |a August, J. Thomas. 
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700 1 |a Murad, Ferid. 
776 0 8 |i Print version:  |t Advances in pharmacology. Volume 22.  |d San Diego : Academic Press : Harcourt Brace Jovanovich, �1991  |z 0120329220  |z 9780120329229  |w (OCoLC)25660610 
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