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Animal models of movement disorders /
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientist...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Burlington, MA :
Elsevier Academic Press,
�2005.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Animal models of movement disorders / |c [edited by] Mark S. LeDoux. |
| 260 | |a Burlington, MA : |b Elsevier Academic Press, |c �2005. | ||
| 300 | |a 1 online resource (xiv, 806 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 520 | |a The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. * Provides a single comprehensive resource on animal models of movement disorders that academic clinicians, translational researchers, and basic neuroscientists can refer to * Includes contributions by expert movement disorder clinicians and top-level researchers in the field * Features a DVD containing over 170 video clips of human movement disorders and the corresponding animal models. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Preface; List of Contributors; A1: Classification and Clinical Features of Movement Disorders; A2: Animal Models and the Science of Movement Disorders; A3: Generation of Transgenic and Gene-Targeted Mouse Models of Movement Disorders; A4: Genetics of Spontaneous Mutations in Mice; A5: Assessment of Movement Disorders in Rodents; A6: Response Dynamics: Measurement of the Force and Rhythm of Motor Responses in Laboratory Animals; A7: Behavior in Drosophila : Analysis and Control; A8: Use of C. elegans to Model Human Movement Disorders; B1: The Phenotypic Spectrum of Parkinson Disease. | |
| 505 | 8 | |a B2: MPTP-Induced Nigrostriatal Injury in Nonhuman PrimatesB3: From Man to Mouse: The MPTP Model of Parkinson Disease; B4: Rotenone Rat and Other Neurotoxin Models of Parkinson Disease; B5: Drosophila Models of Parkinson Disease; B6: Phenotypical Characterization of Genetic Mouse Models of Parkinson Disease; B7: Utility of 6-Hydroxydopamine Lesioned Rats in the Preclinical Screening of Novel Treatments for Parkinson Dise. | |
| 650 | 0 | |a Movement disorders |x Animal models. | |
| 650 | 0 | |a Movement disorders. | |
| 650 | 0 | |a Diseases |x Animal models. | |
| 650 | 1 | 2 | |a Movement Disorders |0 (DNLM)D009069 |
| 650 | 2 | 2 | |a Disease Models, Animal |0 (DNLM)D004195 |
| 650 | 6 | |a Troubles moteurs. |0 (CaQQLa)201-0016038 | |
| 650 | 6 | |a Maladies |x Mod�eles animaux. |0 (CaQQLa)201-0067878 | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Alzheimer's & Dementia. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Neurology. |2 bisacsh | |
| 650 | 7 | |a Movement disorders. |2 fast |0 (OCoLC)fst01028493 | |
| 650 | 7 | |a Diseases |x Animal models. |2 fast |0 (OCoLC)fst00895160 | |
| 650 | 7 | |a Movement disorders |x Animal models. |2 fast |0 (OCoLC)fst01751726 | |
| 655 | 4 | |a Internet Resources. | |
| 700 | 1 | |a LeDoux, Mark. | |
| 776 | 0 | 8 | |i Print version: |t Animal models of movement disorders. |d Burlington, MA : Elsevier Academic Press, �2005 |z 0120883821 |z 9780120883820 |w (DLC) 2004059730 |w (OCoLC)56662019 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120883820 |z Texto completo |