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Advances in DNA sequence specific agents : a research annual. Volume 2 /

DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA seque...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hurley, Laurence H. (�ed.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Greenwich (Connecticut) ; London : Jai Press, 1996.
Colección:Advances in DNA sequence specific agents ; vol. 2
Temas:
Acceso en línea:Texto completo
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MARC

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245 0 0 |a Advances in DNA sequence specific agents :  |b a research annual.  |n Volume 2 /  |c editor Laurence H. Hurley. 
260 |a Greenwich (Connecticut) ;  |a London :  |b Jai Press,  |c 1996. 
300 |a 1 online resource (xi, 347 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 0 |a Advances in DNA sequence specific agents ;  |v vol. 2 
520 |a DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of <IT>Advances in DNA Sequence Specific Agents</IT>. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA. This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition. 
505 0 |a List of Contributors. Preface Part I: Methods used to evaluate the molecular basis for sequence specificity. Part II: Sequence Specificity of DNA Interactive Drugs. 
504 |a Bibliogr. Index. 
588 0 |a Print version record. 
650 0 |a Nucleotide sequence. 
650 0 |a DNA. 
650 0 |a Molecular recognition. 
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650 7 |a Molecular recognition  |2 fast  |0 (OCoLC)fst01024829 
650 7 |a Nucleotide sequence  |2 fast  |0 (OCoLC)fst01041106 
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650 7 |a G&#xFFFD;en&#xFFFD;etique biochimique.  |2 fmesh 
650 7 |a G&#xFFFD;enie g&#xFFFD;en&#xFFFD;etique.  |2 fmesh 
700 1 |a Hurley, Laurence H.,  |e &#xFFFD;ed. 
776 0 8 |i Print version:  |t Advances in DNA sequence specific agents.  |d Greenwich (Connecticut) ; London : Jai Press, 1996  |z 1559381663  |z 9781559381666  |w (OCoLC)40941430 
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