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Bisphosphonates in bone disease : from the laboratory to the patient /

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mech...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Fleisch, Herbert
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �2000.
Edición:4th ed.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Fleisch, Herbert. 
245 1 0 |a Bisphosphonates in bone disease :  |b from the laboratory to the patient /  |c Herbert Fleisch. 
250 |a 4th ed. 
260 |a San Diego :  |b Academic Press,  |c �2000. 
300 |a 1 online resource (xii, 212 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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520 |a This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs. 
505 0 |a Bone and Mineral Metabolism: -- Bone Physiology: -- Morphology. -- Composition of bone. -- Modeling and remodeling. -- Calcium homeostasis. -- Bone as an organ. -- Assessment of bone turnover. -- Bisphosphonates-Preclinical: -- Background to the pharmacological development: -- Chemistry. -- Actions. -- Physicochemical effects. -- Biological effects. -- Inhibition of bone resorption. -- Inhibition of mineralization. -- Pharmocokinetics: -- Intestinal absorption. -- Distribution. -- Renal clearance. -- Other modes of application. -- Animal toxicology: -- Acute toxicology. -- Nonacute toxicology. -- Bisphosphonates-clinical: -- Introduction. -- Paget's Disease: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteolytic tumor-induced bone disease: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Non-tumor induced hypercalcemia: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteoporosis: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Heterotopic calcification and ossification: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Other diseases: -- Adverse events: -- Bisphosphonates in general. -- Individual bisphosphonates. -- Contraindications. -- Future prospects. -- Commercially available bisphosphonates: -- Index. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
650 0 |a Diphosphonates  |x Therapeutic use. 
650 0 |a Bones  |x Diseases  |x Chemotherapy. 
650 1 2 |a Bone Diseases  |x drug therapy  |0 (DNLM)D001847Q000188 
650 1 2 |a Bone Diseases  |x metabolism  |0 (DNLM)D001847Q000378 
650 2 2 |a Diphosphonates  |x pharmacology  |0 (DNLM)D004164Q000494 
650 2 2 |a Diphosphonates  |x therapeutic use  |0 (DNLM)D004164Q000627 
650 6 |a Diphosphonates  |0 (CaQQLa)201-0193190  |x Emploi en th�erapeutique.  |0 (CaQQLa)201-0373975 
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650 7 |a MEDICAL  |x Rheumatology.  |2 bisacsh 
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650 7 |a Diphosphonates  |x Therapeutic use.  |2 fast  |0 (OCoLC)fst00894141 
650 7 |a Diphosphonate  |2 gnd  |0 (DE-588)4150083-0 
650 7 |a Knochenkrankheit  |2 gnd  |0 (DE-588)4120576-5 
776 0 8 |i Print version:  |a Fleisch, Herbert.  |t Bisphosphonates in bone disease.  |b 4th ed.  |d San Diego : Academic Press, �2000  |z 0122603710  |z 9780122603716  |w (DLC) 00100337  |w (OCoLC)43905464 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780122603716  |z Texto completo