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Liver regeneration and carcinogenesis : molecular and cellular mechanisms /
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have oc...
| Cote: | Libro Electrónico |
|---|---|
| Autres auteurs: | |
| Format: | Électronique eBook |
| Langue: | Inglés |
| Publié: |
San Diego :
Academic Press,
�1995.
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| Sujets: | |
| Accès en ligne: | Texto completo |
Table des matières:
- Liver Regeneration, Then and Now. Hepatocyte Growth Factor (HGF) and Its Receptor (MET) in Liver Regeneration, Neoplasia, And Disease. Structure and Functions of the HGF Receptor (C-Met). Expression and Function of Growth-Induced Genes During Liver Regeneration. Stem Cells and Hepatocarcinogenesis. Contributions of Hepadnavirus Research to Our Understanding of Hepatocarcinogenesis. Apoptosis and Hepatocarcinogenesis. Liver Tumor Promotion and the Suppression of P53-Dependant Cell Cycle Checkpoint Function. Mechanisms of Liver Tumor Promotion. Hypomethylation of DNA: A Epigenetic Mechanism that Can Facilitate the Aberrant Oncogene Expression Involved in Liver Carcinogenesis. Transgene-Based Strategies for Studying Liver Growth, Development and Cancer. Subject Index.