Ex vivo cell therapy /

Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Schindhelm, Klaus, Nordon, Robert
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1999.
Temas:
Cellular therapy.
Hematopoietic stem cells > Transplantation.
Gene therapy.
Immunotherapy.
Genetic Therapy
Hematopoietic Stem Cell Transplantation
Immunotherapy
Cell- and Tissue-Based Therapy
Th�erapie cellulaire.
Cellules souches h�ematopo�i�etiques > Greffe.
Th�erapie g�enique.
Immunoth�erapie.
Gene therapy
Cellular therapy
Hematopoietic stem cells > Transplantation
Histoth�erapie.
Greffe de cellules souches h�ematopo�i�etiques.
gentherapie
gene therapy
therapie
therapy
behandeling
treatment
humane ziekten
human diseases
celkweek
cell culture
bloedvorming
haematopoiesis
embryonale stamcellen
embryonic stem cells
transplantatie
transplantation
celbiologie
cellular biology
Pharmacology
Human Pathology
Farmacologie
Humane pathologie
Acceso en línea:Texto completo
Tabla de Contenidos:
  • R.E. Nordon and K. Schindhelm, Introduction.
  • L. Robb, A.G. Elefanty, and C.G. Begley, Transcriptional Control of Hematopoieses.
  • R. Starr and N.A. Nicola, Cell Signaling by Hemopoietic Growth Factor Receptors.
  • P.J. Simmons, D.N. Haylock, and J.-P. L�evesque, Influence of Cytokines and Adhesion Molecules on Hematopoietic Stem Cell Development.
  • P.A. Rowlings, Allogeneic Hematopoietic Stem Cell Transplantation.
  • U. Hahn and L.B. To, Autologous Stem Cell Transplantation.
  • M.R. Vowels, Cord Blood Stem Cell Transplantation.
  • S.R. Riddell, E.H. Warren, D. Lewinsohn, C. Yee, and P.D. Greenberg, Reconstitution of Immunity by Adoptive Immunotherapy with T Cells.
  • L.Q. Sun, M. Miller, and G. Symonds, Exogenous Gene Transfer into Lymphoid and Hematopoietic Progenitor Cells.
  • C. Dowding, T. Leemhuis, A. Jakubowski, and C. Reading, Process Development for Ex Vivo Cell Therapy.
  • R.E. Nordon and K. Schindhelm, Cell Separation.
  • P.W. Zandstra, C.J. Eaves, and J.M. Piret, Environmental Requirements of Hematopoietic Progenitor Cells in Ex Vivo Expansion Systems.
  • R. Mandalam, M. Koller, and A. Smith, Ex Vivo Hematopoietic Cell Expansion for Bone Marrow Transplantation.
  • M. Raponi and G. Symonds, Gene Delivery Technology: Nonviral and Viral Vector Systems.
  • R.E. Nordon and K. Schindhelm, Summary and Future Directions.
  • Index.
  • Sec. 1. Introduction
  • Sec. 2. Transcriptional control of hematopoiesis
  • Sec. 3. Cell signaling by hematopoietic growth factor receptors
  • Sec. 4. Influence of cytokines and adhesion molecules on hematopoietic stem cell development
  • Sec. 5. Allogeneic hematopoietic stem cell transplantation
  • Sec. 6. Autologous stem cell transplantation
  • Sec. 7. Cord blood stem cell transplantation
  • Sec. 8. Reconstitution of immunity by adoptive immunotherapy with T cells
  • Sec. 9. Exogenous gene transfer into lymphoid and hematopoietic progenitor cells
  • Sec. 10. Process development for ex vivo cell therapy
  • Sec. 11. Cell separation
  • Sec. 12. Environmental requirements of hematopoietic progenitor cells in ex vivo expansion systems
  • Sec. 13. Ex vivo hematopoietic cell expansion for bone marrow transplantation
  • Sec. 14. Gene delivery technology: nonviral and viral vector systems
  • Sec. 15. Summary and future directions.

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