Cargando…
In vitro methods in pharmaceutical research /
In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1997.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn162129121 | ||
| 003 | OCoLC | ||
| 005 | 20231117014751.0 | ||
| 006 | m o d | ||
| 007 | cr cn||||||||| | ||
| 008 | 070802s1997 caua ob 001 0 eng d | ||
| 040 | |a OPELS |b eng |e pn |c OPELS |d OPELS |d OCLCQ |d N$T |d IDEBK |d E7B |d OCLCQ |d OCLCF |d YDXCP |d OCLCQ |d YDX |d OCLCO |d OCLCQ |d CASUM |d OCLCA |d STF |d D6H |d OCLCO |d OCLCQ |d OCLCA |d LEAUB |d OCLCO |d OL$ |d OCLCA |d OCLCQ |d OCLCO |d COM |d OCLCQ |d OCL |d OCLCQ |d INARC | ||
| 019 | |a 269472923 |a 646754675 |a 823835440 |a 823903757 |a 824093746 |a 824145866 |a 989249767 |a 1011220259 |a 1027506735 |a 1035655647 |a 1119415287 | ||
| 020 | |a 9780121633905 | ||
| 020 | |a 012163390X | ||
| 020 | |a 9780080534602 |q (electronic bk.) | ||
| 020 | |a 0080534600 |q (electronic bk.) | ||
| 020 | |a 1281466816 | ||
| 020 | |a 9781281466815 | ||
| 035 | |a (OCoLC)162129121 |z (OCoLC)269472923 |z (OCoLC)646754675 |z (OCoLC)823835440 |z (OCoLC)823903757 |z (OCoLC)824093746 |z (OCoLC)824145866 |z (OCoLC)989249767 |z (OCoLC)1011220259 |z (OCoLC)1027506735 |z (OCoLC)1035655647 |z (OCoLC)1119415287 | ||
| 050 | 4 | |a RS122 |b .I52 1997 | |
| 060 | 4 | |a 1996 M-025 | |
| 060 | 4 | |a QV 602 |b I348 1997 | |
| 072 | 7 | |a MED |x 071000 |2 bisacsh | |
| 072 | 7 | |a MMGT |2 bicssc | |
| 082 | 0 | 4 | |a 615.7 |2 22 |
| 245 | 0 | 0 | |a In vitro methods in pharmaceutical research / |c edited by Jos�e V. Castell and Mar�ia Jos�e G�omez-Lech�on. |
| 260 | |a San Diego : |b Academic Press, |c �1997. | ||
| 300 | |a 1 online resource (ix, 467 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies. Key Features * Meets the continuing demand for information in this field * Compares In Vitro techniques with other methods * Describes cell-culture methods used to investigate toxicity in cells derived from different organs * Includes contributions by leading experts in the field. | ||
| 505 | 0 | |a D.W. Straughan, J.H. Fentem, and M. Balls, Replacement Alternative and Complementary In Vitro Methods in Pharamaceutical Research. -- M.D. Barratt and M. Chamberlain, Integration of QSAR and In Vitro Toxicology. -- F.A. Barile, Continuous Cell Lines as a Model for Drug Toxicity Assessment. -- P. Bach, In Vitro Models for Nephrotoxicity Studies. -- A.E.M. Vickers, Experimental In Vitro Models to Evaluate Hepatotoxicity. -- M.J. Gomez-Lechon, T. Donato, X. Ponsoda, R. Fabra, R. Trullenque, and J.V. Castell, Isolation, Culture and Use of Human Hepatocytes in Drug Research. -- E. McFarlane-Abdulla, and I.C. Campbell, Studies of Nephrotoxicity in Cellular Studies. -- M. Adolphe, S. Thenet-Gauci, and S. Demignot, Chondrocyte Culture: A Target System to Evaluate Pharmaco-Toxicological Effects of Drugs. -- E. Chacon, D. Acosta, and J.J. Lemasters, Primary Cultures of Cardiac Myocytes as In Vitro Models for Pharmacological and Toxicological Assessments. -- R. Roguet, Cutaneous Pharmacotoxicology In Vitro. -- H. Spielmann, Ocular Irritation. -- M.A. Miranda, Phototoxicity of Drugs. -- I. de G. Mitchell and R.D. Combes, In Vitro Genotoxicity and Cell Transformation Assessment. -- B. Schmid, R. Bechter, and P. Kucera, The Use of Whole Embryo Cultures in In Vitro Teratogenicity Testing. -- J.V. Castell, M.J. Gomez-Lechon, X. Ponsoda, and R. Bort, In Vitro Investigation of the Molecular Mechanisms of Hepatotoxicity. -- A. Guillouzo, Biotransformation of Drugs by Hepatocytes. -- K. Mace, E.A. Offord, and A.M.A. Pfeifer, Drug Metabolism and Carcinogen Activation Studies with Human Genetically Engineered Cells. | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Drugs |x Research. | |
| 650 | 0 | |a Pharmacy |x Research. | |
| 650 | 0 | |a Drugs |x Side effects. | |
| 650 | 1 | 2 | |a Drug-Related Side Effects and Adverse Reactions |0 (DNLM)D064420 |
| 650 | 1 | 2 | |a Toxicity Tests |0 (DNLM)D018675 |
| 650 | 2 | 2 | |a Cells, Cultured |x drug effects |0 (DNLM)D002478Q000187 |
| 650 | 6 | |a M�edicaments |x Recherche. |0 (CaQQLa)201-0042439 | |
| 650 | 6 | |a M�edicaments |x Effets secondaires. |0 (CaQQLa)201-0002241 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Side effects. |2 fast |0 (OCoLC)fst00898912 | |
| 650 | 7 | |a Drugs |x Research. |2 fast |0 (OCoLC)fst00898894 | |
| 650 | 7 | |a Pharmacy |x Research. |2 fast |0 (OCoLC)fst01060314 | |
| 650 | 1 | 7 | |a In-vitro-onderzoek. |2 gtt |
| 650 | 1 | 7 | |a Farmacie. |2 gtt |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Castell, Jos�e V. | |
| 700 | 1 | |a G�omez-Lech�on, Mar�ia Jos�e. | |
| 776 | 0 | 8 | |i Print version: |t In vitro methods in pharmaceutical research. |d San Diego : Academic Press, �1997 |z 012163390X |z 9780121633905 |w (OCoLC)36003357 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780121633905 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780121633905 |z Texto completo |