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Antigenic variation /

The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process,...

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Bibliographic Details
Call Number:Libro Electrónico
Other Authors: Craig, Alister G., Scherf, Artur
Format: Electronic eBook
Language:Inglés
Published: London ; San Diego : Academic Press, �2003.
Subjects:
Online Access:Texto completo
Description
Summary:The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body. The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour. Comprehensive coverage of antigenic variation from viruses to parasites Discussions devoted to molecular mechanisms of host evasion Detailed descriptions of host/pathogen interactions.
Physical Description:1 online resource (xvi, 443 pages) : illustrations
Bibliography:Includes bibliographical references and index.
ISBN:1423755383
9781423755388
9780121948511
012194851X
128100815X
9781281008152
0080475884
9780080475882