Health effects of low doses of radiation : perspectives on integrating radiation biology and epidemiology.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bethesda, Maryland : National Council on Radiation Protection and Measurements, 2015.
Colección:NCRP commentary ; no. 24.
Temas:
Radiation dosimetry.
Radiation > Health aspects.
Radiation > Toxicology.
Radiometry
Dosimétrie.
Rayonnement > Toxicologie.
dosimetry.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Preface; Contents; Executive Summary; 1. Introduction; 1.1 Low Doses and Low Dose Rates; 1.2 Use of Radiation Biology Data to Reduce the Uncertainty in Risk Estimates; 2. General Approaches to Risk Assessment; 2.1 Risk Assessment Process and Associated Uncertainties; 2.2 Modeling Uncertainties: Dosimetric, Epidemiologic and Biological; 2.3 Transfer of Risk Between Populations of Different Countries; 2.4 Extrapolating Low-Dose Effects from In Vitro to In Vivo; Animal to Human; 3. Studies Integrating Biology and Epidemiology; 3.1 Epidemiologic Studies Focused on Cancer Outcomes.
  • 3.1.1 Chromosome Aberration Studies3.1.2 Atomic-Bomb Survivors; 3.1.3 Pelvic Irradiation Studies; 3.1.4 Occupational Studies; 3.1.5 Environmental Background Studies; 3.1.6 Transgenerational Studies; 3.1.7 Gene and Radiation Interaction: The Women's Environmental Cancer and Radiation Epidemiology Study; 3.1.8 Retinoblastoma; 3.2 Epidemiologic Studies Focused on Noncancer Outcomes; 4. Bioindicators from Radiation Biology Studies; 4.1 DNA Damage and Repair; 4.2 Signaling of DNA Damage at Low Doses; 4.3 Chromosome Alterations; 4.4 Mutations; 4.5 Radiation-Induced Genomic Instability.
  • 4.6 Modulators of Response4.6.1 Adaptive Responses; 4.6.2 Bystander Effects; 4.6.3 Genetic Susceptibility and Interactions with Radiation; 4.6.4 Interactions with Environmental and Lifestyle Factors; 5. Closing the Gaps Towards an Integrated Approach; 5.1 Targeted Research to Identify Adverse Outcome Pathways and Bioindicators of Response; 5.2 Biologically Based Modeling; 5.2.1 Biologically Based Dose-Response Approach; 5.2.2 Systems Biology; 5.3 Registries of Medical-Imaging Exposures Linked to Outcomes and Biological Materials; 5.4 Facilities and Interdisciplinary Training; 5.4.1 Facilities.
  • 5.4.2 Interdisciplinary TrainingAbbreviations and Acronyms; Glossary; References; Scientific Committee Members; NCRP Commentaries.

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