Drug-like properties : concepts, structure design and methods from ADME to toxicity optimization /

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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will succes...

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Bibliographic Details
Call Number:Libro Electrónico
Main Authors: Di, Li (Author), Kerns, Edward Harvel (Author)
Format: Electronic eBook
Language:Inglés
Published: Amsterdam : Elsevier, [2016]
Edition:Second edition.
Subjects:
Pharmaceutical chemistry.
Drugs > Structure-activity relationships.
Drug development.
Drugs > Design.
Chemistry, Pharmaceutical
Drug Design
Chimie pharmaceutique.
Médicaments > Relations structure-activité.
Médicaments > Développement.
Médicaments > Conception.
MEDICAL / Pharmacology
Drug development
Drugs > Design
Drugs > Structure-activity relationships
Pharmaceutical chemistry
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