Cargando…

Sequence-specific DNA binding agents /

The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Waring, Michael J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge : RSC Pub., ©2006.
Colección:RSC biomolecular sciences.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000 a 4500
001 KNOVEL_ocn649978215
003 OCoLC
005 20231027140348.0
006 m o d
007 cr un||||a|a||
008 100723s2006 enka ob 001 0 eng d
040 |a OCLCE  |b eng  |e pn  |c OCLCE  |d COO  |d OCLCQ  |d E7B  |d OCLCO  |d OCLCF  |d KNOVL  |d OCLCQ  |d OCLCO  |d ZCU  |d KNOVL  |d YDXCP  |d OCLCQ  |d BUF  |d RRP  |d WYU  |d OCLCO  |d OCLCA  |d OCLCQ  |d OCLCO  |d HS0  |d ERF  |d UKBTH  |d LIP  |d OCLCQ  |d OCLCA  |d OCLCQ  |d OCLCA  |d AGLDB  |d UX1  |d MM9  |d OCLCQ  |d LVT  |d OCLCQ  |d OCLCO  |d OCLCQ 
015 |a GBA684662  |2 bnb 
016 7 |a 013565126  |2 Uk 
019 |a 468774292  |a 560363707  |a 1066452075  |a 1109269502  |a 1112925999  |a 1120857775  |a 1146469544  |a 1152036995  |a 1159642500  |a 1229671420 
020 |a 9781628701395  |q (electronic bk.) 
020 |a 1628701390  |q (electronic bk.) 
020 |a 1847555306 
020 |a 9781847555304 
020 |z 9780854043705 
020 |z 0854043705 
029 1 |a AU@  |b 000051343284 
029 1 |a GBVCP  |b 856586684 
029 1 |a NZ1  |b 15500645 
035 |a (OCoLC)649978215  |z (OCoLC)468774292  |z (OCoLC)560363707  |z (OCoLC)1066452075  |z (OCoLC)1109269502  |z (OCoLC)1112925999  |z (OCoLC)1120857775  |z (OCoLC)1146469544  |z (OCoLC)1152036995  |z (OCoLC)1159642500  |z (OCoLC)1229671420 
042 |a dlr 
050 4 |a QP624.75.D77  |b S46 2006 
060 4 |a 2007 A-525 
060 4 |a QU 58.5  |b S4795 2006 
082 0 4 |a 616.994061  |2 22 
084 |a VS 5350  |2 rvk 
049 |a UAMI 
245 0 0 |a Sequence-specific DNA binding agents /  |c edited by Michael Waring. 
260 |a Cambridge :  |b RSC Pub.,  |c ©2006. 
300 |a 1 online resource (xi, 258 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a RSC biomolecular sciences 
504 |a Includes bibliographical references and index. 
505 0 |a DNA recognition by triple helix formation / David A. Rusling, Tom Brown, and Keith R. Fox -- Interfacial inhibitors of human topoisomerase I / Christophe Marchand and Yves Pommier -- Diversity of topoisomerase I inhibitors for cancer chemotherapy / Nathalie Dias and Christian Bailly -- Slow DNA binding / L. Marcus Wilhelmsson, Per Lincoln, and Bengt Nordén -- DNA gene targeting using Peptide Nucleic Acid (PNA) / Peter E. Nielsen -- Actinomycin D : sixty years of progress in characterizing a sequence-selective DNA-binding agent / David E. Graves -- Thermal denaturation of drug-DNA complexes : tools and tricks / Jonathan B. Chaires and Xiaochun Shi -- Computer simulations of drug-DNA interactions : a personal journey / Federico Gago -- The discovery of G-quadruplex telomere targeting drugs / Stephen Neidle -- The mechanism of action of telomestatin, a G-quadruplex-interactive compound / Daekyu Sun and Laurence H. Hurley -- Structural features of the specific interactions between nucleic acids and small organic molecules / Alexander Serganov and Dinshaw J. Patel. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
583 1 |a digitized  |c 2010  |h HathiTrust Digital Library  |l committed to preserve  |2 pda  |5 MiAaHDL 
588 0 |a Print version record. 
520 |a The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by experts in the field, this book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment. Chapters discuss established agents like actinomycin D but also look at novel drugs with strong potential in chemotherapy suc. 
546 |a English. 
590 |a Knovel  |b ACADEMIC - Pharmaceuticals, Cosmetics & Toiletries 
650 0 |a DNA-drug interactions. 
650 0 |a DNA-binding proteins. 
650 0 |a Gene targeting. 
650 0 |a Drug targeting. 
650 0 |a Chemotherapy. 
650 1 2 |a DNA-Binding Proteins  |x therapeutic use 
650 2 2 |a Chemistry, Pharmaceutical  |x methods 
650 2 2 |a DNA  |x drug effects 
650 2 2 |a DNA  |x metabolism 
650 2 2 |a DNA-Binding Proteins  |x chemistry 
650 2 2 |a DNA-Binding Proteins  |x metabolism 
650 2 |a DNA-Binding Proteins 
650 2 |a Gene Targeting 
650 2 |a Drug Delivery Systems 
650 2 |a Drug Therapy 
650 6 |a Interactions ADN-médicament. 
650 6 |a Protéines de liaison à l'ADN. 
650 6 |a Gènes  |x Ciblage. 
650 6 |a Médicaments  |x Ciblage. 
650 6 |a Chimiothérapie. 
650 7 |a Chemotherapy.  |2 fast  |0 (OCoLC)fst00853595 
650 7 |a DNA-binding proteins.  |2 fast  |0 (OCoLC)fst00886613 
650 7 |a DNA-drug interactions.  |2 fast  |0 (OCoLC)fst00886614 
650 7 |a Drug targeting.  |2 fast  |0 (OCoLC)fst00898709 
650 7 |a Gene targeting.  |2 fast  |0 (OCoLC)fst00939637 
700 1 |a Waring, Michael J. 
776 0 8 |i Print version:  |w (DLC) 2007360567  |w (OCoLC)72867758 
830 0 |a RSC biomolecular sciences. 
856 4 0 |u https://appknovel.uam.elogim.com/kn/resources/kpSSDNABA3/toc  |z Texto completo 
938 |a ebrary  |b EBRY  |n ebr10626623 
938 |a YBP Library Services  |b YANK  |n 9897961 
994 |a 92  |b IZTAP