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NMR spectroscopy in pharmaceutical analysis /

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatograph...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Holzgrabe, U. (Ulrike), Wawer, I. (Iwona), Diehl, B. (Bernd)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, ©2008.
Edición:1st ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • pt. I. Fundamentals and techniques. Principles in NMR spectroscopy / B. Diehl ; Quantitative NMR in the solution state NMR / F. Malz ; qNMR in solid state / I. Wawer ; Microcoil nuclear magnetic resonance spectroscopy / A.G. Webb ; qNMR spectroscopy in drug analysis
  • a general view / U. Holzgrabe
  • pt. II. General applications. Investigation of multi-component drugs by NMR spectroscopy / T. Beyer and U. Holzgrabe ; NMR applications for polymer characterization / B. Diehl ; NMR spectroscopy of natural substances / B. Diehl ; Solid-state measurements of drugs and drug formulations / I. Wawer ; Metabolic profiling / K.A. Kaiser [and others] ; DOSY NMR for drug analysis / V. Gilard [and others] ; The use of qNMR for the analysis of agrochemicals / R.J. Wells, J. Cheung, and (in part) J.M. Hook
  • pt. III. Special applications. NMR-based mixture analysis on the example of fruit juice quality control using statistics and quantification / M. Spraul [and others] ; NMR assays for carbohydrate-based vaccines / C. Jones and N. Ravenscroft ; Fluorine-19 or Phosphorus-31 NMR spectroscopy : a powerful technique for biofluid metabolic studies and pharmaceutical formulation analysis of fluorinated or phosphorylated drugs / R. Martino, V. Gilard, and M. Malet-Martino ; Quantitative 2D NMR analysis of glycosaminoglycans / G. Torri and M. Guerrini ; The use of proton NMR as an alternative for the amino acid analysis as identity test for peptides / E. Kellenbach, K. Sander, and P.L.A. Overbeeke ; Assessment of inhibitory potency of antibiotics by MRI / C. Faber ; Hypernation and concatenation : multiple on-line spectroscopic analysis for drug and natural product characterisation / I.D. Wilson ; Quantitative high-resolution online NMR spectroscopy in pharmaceutical reaction and process monitoring / M. Maiwald [and others].