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Systems biology : properties of reconstructed networks /

The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemist...

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Bibliographic Details
Call Number:Libro Electrónico
Main Author: Palsson, Bernhard
Format: Electronic eBook
Language:Inglés
Published: Cambridge ; New York : Cambridge University Press, 2006.
Subjects:
Online Access:Texto completo
Table of Contents:
  • 1. Introduction
  • 2. Basic concepts in systems biology
  • 3. Metabolic networks
  • 4. Transcriptional regulatory networks
  • 5. Signaling networks
  • 6. Basic features of the stoichiometric matrix
  • 7. Topological properties
  • 8. Fundamental subspaces of S
  • 9. The (right) null space of S
  • 10. The left null space of S
  • 11. The row and column spaces of S
  • 12. Dual causality
  • 13. Properties of solution spaces
  • 14. Sampling solution spaces
  • 15. Finding functional states
  • 16. Parametric sensitivity
  • 17. Epilogue.