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Nanoparticle enhanced radiation therapy : principles, methods and applications /

Improved targeting of abnormal cells and tissue in the radiotherapy of cancer has been a long-standing goal of researchers. The central purpose in Nanoparticle-Enhanced Radiotherapy (NPRT) is to more precisely control where the radiation dose is delivered, desirably with subcellular precision, provi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Sajo, Erno (Editor ), Zygmansk, Piotr (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2020]
Colección:IOP series in global health and radiation oncology.
IOP ebooks. 2020 collection.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Nanoparticle enhanced radiation therapy :  |b principles, methods and applications /  |c edited by Erno Sajo, Piotr Zygmansk. 
264 1 |a Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :  |b IOP Publishing,  |c [2020] 
300 |a 1 online resource (various pagings) :  |b illustrations (some color). 
336 |a text  |2 rdacontent 
337 |a electronic  |2 isbdmedia 
338 |a online resource  |2 rdacarrier 
490 1 |a IOP series in global health and radiation oncology 
490 1 |a IOP ebooks. [2020 collection] 
500 |a "Version: 20201101"--Title page verso. 
504 |a Includes bibliographical references. 
505 0 |a part I. Radiosensitization and fundamentals. 1. The role of Auger electrons versus photoelectrons in nanoparticle dose enhancement / Erno Sajo and Piotr Zygmanski -- 2. Deterministic computation benchmarks of nanoparticle dose enhancement--part I. Nanometer scales / Erno Sajo, Fulya Cifter and Piotr Zygmanski -- 3. Deterministic computation benchmarks of nanoparticle dose enhancement--part II. Microscopic to macroscopic scales / Erno Sajo, Fulya Cifter and Piotr Zygmanski -- 4. Mechanisms of low energy electron interactions with biomolecules : relationship to gold nanoparticle radiosensitization / Yi Zheng and Léon Sanche -- 5. Monte Carlo models of electron transport for dose-enhancement calculations in nanoparticle-aided radiotherapy / Dimitris Emfietzoglou and Sebastien Incerti -- 6. Nanoparticle-aided radiation therapy : challenges of treatment planning / C. Kirkby and B. Koger -- 7. Nanoparticle enhanced radiotherapy : quality assurance perspective / Piotr Zygmanski, Davide Brivio and Erno Sajo -- 8. Optimal nanoparticle concentrations, toxicity and safety and gold nanoparticle design for radiation therapy applications / Rajiv Kumar and Wilfred Ngwa -- 9. Translational nanomaterials for cancer radiation therapy / Shady Kotb and Sijumon Kunjachan -- 10. Gold nanoparticle enhanced radiosensitivity of cells : considerations and contradictions from model systems and basic investigations of cell damaging for radiation therapy / Martin Falk, Michael Wolinsky, Marlon R. Veldwijk, Georg Hildenbrand and Michael Hausmann -- part II. Imaging. 11. Super-resolution microscopy of nanogold-labelling / Michael Hausmann, Götz Pilarczyk, Emanuel Maus, Jürgen Hesser and Georg Hildenbrand -- 12. X-ray based nanoparticle imaging / Juergen Hesser and Davide Brivio -- 13. MRI based nanoparticle imaging / Frank G. Zöllner -- 14. Nanoparticle detection using photoacoustic imaging (PAI) / Romy Mueller, Wilfred Ngwa and Juergen Hesser -- part III. Applications. 15. Radiotherapy application with in situ dose-painting (RAiD) via inhalation delivery / Yao Hao -- 16. High-Z ORAYA therapy for wet AMD and ocular cancers / Yucel Altundal and Wilfred Ngwa -- 17. Cerium oxide and titanium dioxide / Zi Ouyang and Wilfred Ngwa -- 18. Accelerated Partial Breast Irradiation (APBI) / Gizem Cifter and Wilfred Ngwa. 
520 3 |a Improved targeting of abnormal cells and tissue in the radiotherapy of cancer has been a long-standing goal of researchers. The central purpose in Nanoparticle-Enhanced Radiotherapy (NPRT) is to more precisely control where the radiation dose is delivered, desirably with subcellular precision, provided we can find a method to bring the nanoparticles to target and control their concentration and size distribution. The contents within this book will cover the rationale and fundamental principles of NPRT, optimal nanoparticle sizes, concentrations, design and fabrication, effective nanoparticle delivery methods, emerging clinical applications of NRT modalities, treatment planning and quality assurance and the potential of NPRT in global health. This volume will serve as a resource for researchers, educators and industry, and as a practical guide or comprehensive reference for students, research trainees and others working in cancer nanomedicine. Part of IOP Series in Global Health and Radiation Oncology. 
521 |a Researchers in nanomedicine, radiation oncology and radiology. 
530 |a Also available in print. 
538 |a Mode of access: World Wide Web. 
538 |a System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. 
545 |a Erno Sajo, PhD, is a Professor and Director of Medical Physics at the University of Massachusetts Lowell, where he also serves as the Director of Biomedical Engineering and Biotechnology. His research areas are radiation transport computations at the nanoscale with emphasis on interfacial effects, including nanoparticle transport, the physiological translocation of nanoparticles, and nanoparticle enhanced radiation therapy. He is an associate editor of the Health Physics Journal and has also served as ad-hoc editor of Medical Physics. Piotr Zygmanski, PhD, is Associate Professor of Radiation Oncology at the Harvard Medical School and Medical Physicist at the Brigham and Women's Hospital/Dana Farber Cancer Institute, Boston, Massachusetts. Prior to his present position he acquired his clinical training at the Massachusetts General Hospital, and the Harvard Cyclotron Laboratory. His research interests include multiscale radiation transport computations, detection of radiation and mathematical modeling for the standard and nanoparticle enhanced radiotherapy. 
588 0 |a Title from PDF title page (viewed on December 4, 2020). 
650 0 |a Nanoparticles  |x Therapeutic use. 
650 0 |a Cancer  |x Radiotherapy. 
650 1 2 |a Nanoparticles  |x therapeutic use. 
650 1 2 |a Neoplasms  |x radiotherapy. 
650 7 |a Radiotherapy.  |2 bicssc 
650 7 |a MEDICAL / Radiology, Radiotherapy & Nuclear Medicine.  |2 bisacsh 
700 1 |a Sajo, Erno,  |e editor. 
700 1 |a Zygmansk, Piotr,  |e editor. 
710 2 |a Institute of Physics (Great Britain),  |e publisher. 
776 0 8 |i Print version:  |z 9780750323949  |z 9780750323970 
830 0 |a IOP series in global health and radiation oncology. 
830 0 |a IOP ebooks.  |p 2020 collection. 
856 4 0 |u https://iopscience.uam.elogim.com/book/978-0-7503-2396-3  |z Texto completo