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00000cam a2200000Mu 4500 |
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EBSCO_on1231607408 |
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20231017213018.0 |
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210116s2020 xx o ||| 0 eng d |
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|a EBLCP
|b eng
|c EBLCP
|d UKAHL
|d YDX
|d N$T
|d OCLCF
|d OCLCO
|d OCLCQ
|d OCLCO
|d OCLCQ
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|a 1230122413
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|a 9781774079904
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|a 1774079909
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|a (OCoLC)1231607408
|z (OCoLC)1230122413
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|a RB155.8
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|a 616.042
|2 23
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|a UAMI
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|a Kartan, Preethi.
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|a Genetherapy
|h [electronic resource].
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|a Ashland :
|b Delve Publishing,
|c 2020.
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|a 1 online resource (374 p.)
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Description based upon print version of record.
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|a Cover -- Title Page -- Copyright -- DECLARATION -- ABOUT THE EDITOR -- TABLE OF CONTENTS -- List of Contributors -- List of Abbreviations -- Preface -- Chapter 1 Recent Advances in the Development of Gene Delivery Systems -- Abstract -- Background -- Conclusion -- References -- Chapter 2 Cell Penetrating Peptides, Novel Vectors for Gene Therapy -- Abstract -- Introduction -- Types of CPPs -- Identification of Tissue Specific CPPs -- Mechanisms of Transduction -- Cell Penetrating Peptides as Gene Delivery Vectors -- Hurdles to Clinical Application -- Summary -- Patents -- Author Contributions
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|a Funding -- Acknowledgments -- Conflicts of Interest -- References -- Chapter 3 Advances in Viral Vector-Based TRAIL Gene Therapy for Cancer -- Abstract -- Introduction: Trail As An Anti-Cancer Biologic Agent -- Structure And Function of Trail -- The Trail Receptor Family -- Signaling Cascades That Regulate Trail-Induced Apoptosis -- Overcoming Tumor Cell Resistance To Trail-Induced Apoptosis -- Viral Vector-Mediated Gene Therapy -- Conclusions -- Acknowledgements -- References -- Chapter 4 Advances in Lipid Nanoparticles for siRNA Delivery -- Abstract -- Introduction
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8 |
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|a LNP Formulation: Composition, Structure And Size -- Encapsulation And Intracellular Release: Dual Function of Ionizable Amino Lipids -- Steric Barrier: Stability and Circulation Lifetime -- Cellular Uptake: Endogenous and Exogenous Targeting Ligands -- Concluding Remarks -- Acknowledgments -- Conflicts Of Interest -- References -- Chapter 5 Gene Switches for Deliberate Regulation of Transgene Expression: Recent Advances in System Development and Uses -- Abstract -- Introduction -- Small Molecule-Dependent Gene Switches -- Transgene Activation By Focused Heat or Ionizing Radiation
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|a Other Inducible Systems -- Concluding Remarks -- References -- Chapter 6 Simultaneous Administration of ADSCs-Based Therapy and Gene Therapy Using Ad-huPA Reduces Experimental Liver Fibrosis -- Abstract -- Introduction -- Materials And Methods -- Results -- Discussion -- Conclusions -- Funding Statement -- Data Availability -- References -- Chapter 7 Gene Therapy: Advances, Challenges and Perspectives -- Abstract -- Introduction -- Comment -- References -- Chapter 8 Recent Advances in Mitochondria-Targeted Gene Delivery -- Abstract -- Introduction -- Physical Approaches -- Chemical Approaches
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|a Biological Approaches -- Combinatorial Approaches -- Cargo Dnas -- Applications As Disease Therapies -- Concluding Remarks -- Funding -- Conflicts Of Interest -- References -- Chapter 9 Gene Therapy for Cancer: Present Status and Future Perspective -- Abstract -- Introduction -- History -- Methods Of Gene Therapy -- Gene Transfer Delivery System -- Gene Therapy Implementation -- Immunomodulation -- Innate Immunity -- Immunomodulatory Approaches In Cancer Therapy -- Other Gene Therapy Approaches In Cancer Management -- Problems With Gene Therapy -- Review, Conclusions -- Authors' Information
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|a Abbreviations.
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590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
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|a Gene therapy.
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650 |
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|a Genetic Therapy
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650 |
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|a Thérapie génique.
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|a Gene therapy
|2 fast
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776 |
0 |
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|i Print version:
|a Kartan, Preethi
|t Genetherapy
|d Ashland : Delve Publishing,c2020
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856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2725276
|z Texto completo
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938 |
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|a Askews and Holts Library Services
|b ASKH
|n AH38250210
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938 |
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|a ProQuest Ebook Central
|b EBLB
|n EBL6453514
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938 |
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|a EBSCOhost
|b EBSC
|n 2725276
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|a YBP Library Services
|b YANK
|n 301864932
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|a 92
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