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Adipogenesis : signaling pathways, molecular regulation and impact on human disease /

Adipogenesis is the process of cell differentiation by which preadipocytes become adipocytes. Adipogenesis has been one of the most intensively studied models of cellular differentiation. The exact mechanisms of adipogenesis remain unclear, since it involves abundant gene, growth factors, cytokines...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lin, Yunfeng (Editor ), Cai, Xiaoxiao (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical, [2013]
Colección:Cell biology research progress.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ""ADIPOGENESIS ""; ""ADIPOGENESIS ""; ""Library of Congress Cataloging-in-Publication Data ""; ""Contents ""; ""Preface ""; ""Chapter I Molecular Determination of Adipogenic versus Osteogenic Differentiation in Mesenchymal Stem Cells ""; ""Abstract ""; ""Introduction ""; ""Clinical Applications of Mesenchymal Cells ""; ""Transcription Factors""; ""Wnt Signaling ""; ""Hedgehog Signaling""; ""Bone Morphogenetic Protein (BMP) Signaling ""; ""Conclusion ""; ""References ""; ""Chapter II LMNA-Linked Lipodystrophies: Experimental Models to Unravel the Molecular Mechanisms ""; ""Abstract ""
  • ""Lipodystrophies """"The LMNA Gene and the Nuclear Lamina ""; ""Clinical Features and Main Characteristics of Lamina Related Lypodystrophies ""; ""Familial Partial Lipodystrophy, Dunningan Type (FPLD2) ""; ""Mandibuloacral Dysplasia Type A (MADA) ""; ""Mandibuloacral Dysplasia Type B (MADB) ""; ""Hutchinsonâ€?Gilford Progeria Syndrome (HGPS) ""; ""HIV-Related Lipodystrophy""; ""LMNA Murine Models ""; ""Development and Testing of Potential Therapeutic Strategies: The Prenylation Dilemma ""; ""Challenging Mouse to Model Human Lipodystrophy ""
  • ""Adipocyte Differentiation from Mesenchymal Stem Cells """"Human Adipogenesis Cell Models Based on Stem Cells ""; ""A Model of Lipodystrophy Based on Prelamin a Accumulating hMSCs ""; ""Adipogenesis Models Based on Induced Pluripotent Stem Cells (iPSCs) ""; ""Conclusion ""; ""References ""; ""Chapter III Adipogenesis and Osteoblastgenesis toward the Ageing Intervention in the 21st Century ""; ""Abstract ""; ""Abbreviations ""; ""1. Ageing in the World ""; ""2. Teeth and Cognitive Functions in Elderly People""; ""3. Fat and Bone in Elderly People ""
  • ""4. Adipogenesis and Osteoblastgenesis from Mesenchymal Stem Cells""""5. Chemical-Regulated Adipogenesisand Osteoblastgenesis ""; ""6. PPAR in Adipocyte and Runx2 in Osteoblast ""; ""7. Drug (TZD) Regulated Adipogenesis and Osteoblastgenesis ""; ""8. Estrogen Effect on Both Adipogenesis and Osteoblastgenesis ""; ""9. Prostaglandin J2 (PGJ2) Regulate Both Adipogenesis and Osteoblastgenesis ""; ""10. Prostaglandin X2 (PGX2) Regulate Both Adipogenesis and Osteoblastgenesis ""; ""11. Nanotechnology for Identification of Chemical Target Protein""; ""11.1. Arginine ""
  • ""11.2. Prostaglandin J (PGJ2) 2 """"Conclusion ""; ""References ""; ""Chapter IV Role of Wnt/ -Catenin Signaling in Bone Marrow adiposity Following Cancer Chemotherapy ""; ""Abstract ""; ""I. Introduction ""; ""II. Osteogenesis, Adipogenesis, and Regulation by Wnt/ -Catenin Signaling Pathway ""; ""Osteogenesis and Osteogenic Transcription Factors ""; ""Adipogenesis and Adipogenic Transcription Factors and Regulators ""; ""Wnt Signaling Pathway in Osteogenic and Adipogenic Commitment and Differentiation ""