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|a 855505001
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|a Rudin, M.
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|d 1953-
|e author.
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|a Molecular imaging :
|b basic principles and applications in biomedical research /
|c Markus Rudin, University of Zürich, Switzerland.
|
250 |
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|a 2nd edition.
|
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|
1 |
|a London :
|b Imperial College Press,
|c [2013]
|
264 |
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2 |
|a Singapore :
|b World Scientific
|
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|c ©2013
|
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|a 1 online resource (618 pages) :
|b illustrations (some color)
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|a Includes bibliographical references and index.
|
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0 |
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|a Introduction -- Methodologies -- Imaging techniques -- Molecular reporter systems -- Design of molecular imaging probes -- Applications -- Drug imaging -- Imaging gene expression -- Imaging the function of gene products -- Monitoring of cell migration.
|
520 |
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|a This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies. The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts.
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|a Online resource; title from digital title page (ebrary, viewed on December 5, 2014).
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|a English.
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|a Molecular probes.
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|a Diagnostic imaging.
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|a Imaging systems in medicine.
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|a Imagerie pour le diagnostic.
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|a Imagerie médicale.
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|i Print version:
|a Rudin, M. (Markus), 1953-
|t Molecular imaging.
|b 2nd edition.
|d London : World Scientific, [2013]
|z 9781848168565
|w (DLC) 2012046671
|w (OCoLC)828680910
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