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Advances in medicine and biology. Volume 43 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Science Publishers,
©2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ADVANCES IN MEDICINE AND BIOLOGY VOLUME 43; ADVANCES IN MEDICINE AND BIOLOGY VOLUME 43; Contents ; Preface ; Paralysis in ALS Patients Pathogenesis, Assessment and Treatment ; Abstract; Introduction ; Epidemiology ; Sporadic ALS ; Familial ALS ; Etiopathogenesis ; Genetic Factors ; Environmental Factors ; Excitotoxicity ; Oxidative Stress and Apoptosis ; Lack of Neurotrophic Factors ; Immune Events and Neuroinflammation ; Defective Autophagy ; Exogenous Toxicity ; Neuropathology ; Brain ; Brainstem ; Corticospinal Tract ; Spinal Cord ; Peripheral Nervous System; Muscle; Clinical Signs.
- Clinical Features of Variant Disorders Diagnosis ; Clinical Criteria ; Neurophysiological Methods ; Conventional Electromyography ; Nerve Conduction Studies ; Transcranial Magnetic Stimulation ; Neuroimaging Techniques ; Laboratory Exams ; Muscle biopsy ; Biochemical Assays ; Differential Diagnoses ; Functional Assessment; Global Functional Scales ; The Appel ALS Rating Scale ; The ALS Severity Scale (ALSSS) ; ALS Functional Rating Scale ; Somatic Muscle Strength Assessment ; Manual Muscle Testing ; Maximal Voluntary Isometric Contraction ; Quantitative Electromyography.
- Respiratory Muscle Function Assessment Swallowing Assessment ; Speech Assessment ; Treatment; Pathogenetic Treatment ; Neuropharmacological Strategies ; Excitotoxicity ; Oxidative Stress and Apoptosis ; Neurotrophic Factors ; Neuroinflammation ; Autophagy ; Neurobiological Strategies ; Gene Therapy; Stem Cell Therapy ; Neurophysiological Strategies ; Repetitive Transcranial Magnetic Stimulation ; Symptomatic Treatment ; Pharmacological Strategies ; Non Pharmacological Strategies ; Physical Exercise ; Respiratory Treatment; Respiratory Exercises ; Mechanical Ventilation.
- Supportive Respiratory Care Swallowing Treatment ; Sialorrhea ; Speech Treatment ; Conclusion; References; Targeting Testosterone Pathways in Prostate Cancer Treatment ; Abstract ; Biology of Testosterone in Prostate Cancer ; 1. Androgen Synthesis and the Androgen Receptor Regulatory Pathway ; 2. Estrogen Receptors in Prostate Cancer ; 3. Prostate Cancer Prevention ; 1.) Finasteride ; 2.) Dutasteride; Androgen-Deprivation Therapy (ADT) ; 1.) Orchiectomy ; 2.) Estrogen; 3.) GnRH-A ; 4.) GnRH Antagonists ; 5.) Androgen Receptor Antagonists (ARAs) ; 6.) CYP17 Inhibitors; Ketoconazole.
- Abiraterone Acetate TAK-700 (Orteronel) ; 7.) AR Antagonists ; MDV3100 ; BMS-641988 ; Small Molecule Modulators ; 8.) Dual CYP17 Inhibitor and AR Antagonist ; 9.) Glucocorticoids; 2. Early-Stage Prostate Cancer ; 1.) ADT as Primary Therapy ; 2.) ADT with Radiotherapy ; 3.) ADT with Brachytherapy ; 4.) ADT with Surgery ; 3. Metastatic Castration-Sensitive Disease ; 1.) Antiandrogen Monotherapy; 2.) Combined Androgen Blockade ; 3.) ADT with Chemotherapy ; 4.) ADT and Vaccine ; 4. Timing of ADT in Metastatic Castration-Sensitive Prostate Cancer ; 1.) Immediate vs. Deferred Therapy.