Cargando…

MARC

LEADER 00000cam a2200000Mi 4500
001 EBSCO_ocn828140687
003 OCoLC
005 20231017213018.0
006 m o d
007 cr |n|||||||||
008 130220s2012 nyua ob 001 0 eng d
010 |z  2012470307 
040 |a YDXCP  |b eng  |e pn  |c YDXCP  |d OCLCO  |d N$T  |d E7B  |d OCLCF  |d OCLCQ  |d EBLCP  |d OCLCO  |d DEBSZ  |d OCLCQ  |d D6H  |d AGLDB  |d OCLCQ  |d VTS  |d STF  |d OCLCQ  |d VLY  |d AJS  |d DST  |d OCLCO  |d OCLCQ  |d OCL  |d OCLCO 
019 |a 923653835  |a 1162046592  |a 1300652077  |a 1303349561  |a 1303400874 
020 |a 1619428377  |q (electronic bk.) 
020 |a 9781619428379  |q (electronic bk.) 
020 |z 9781619428300 
020 |z 161942830X 
029 1 |a DEBBG  |b BV041049682 
029 1 |a DEBSZ  |b 472771167 
035 |a (OCoLC)828140687  |z (OCoLC)923653835  |z (OCoLC)1162046592  |z (OCoLC)1300652077  |z (OCoLC)1303349561  |z (OCoLC)1303400874 
050 4 |a RC382  |b .P26442 2012 
072 7 |a HEA  |x 039140  |2 bisacsh 
072 7 |a MED  |x 056000  |2 bisacsh 
082 0 4 |a 616.833 
049 |a UAMI 
245 0 0 |a Parkinson's disease :  |b diagnosis, treatment, and prognosis /  |c Chiyo Yoshida and Ami Ito, editors. 
260 |a New York :  |b Nova Science Publishers, Inc.,  |c [2012] 
300 |a 1 online resource (xii, 232 pages :  |b illustrations). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Neurodegenerative Diseases : Laboratory and Clinical Research 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a ""PARKINSON'S DISEASE ""; ""PARKINSON'S DISEASE ""; ""CONTENTS ""; ""PREFACE ""; ""THERAPEUTIC INTERVENTION AT CELLULAR CLEARANCE MECHANISMS: SIGNIFICANCE TO PARKINSONâ€?S DISEASE ""; ""ABSTRACT ""; ""ABBREVIATIONS ""; ""1. INTRODUCTORY REMARKS ""; ""2. INTRACELLULAR CLEARANCE MECHANISMS ""; ""2.1. The Ubiquitin Proteasome System ""; ""2.1.1. Quality Control through the Ubiquitin Proteasome System ""; ""2.1.2. Ubiquitin Proteasome System impairment in PD ""; ""2.2. The Autophagy-Lysosomal Pathway ""; ""2.2.1. Quality Control through the Autophagic- Lysosomal Pathway "" 
505 8 |a ""2.2.2. Autophagy- Lysosomal Pathway dysfunction in PD """"2.3. Enzymatic Proteolytic Systems ""; ""2.3.1. Quality Control through Cytosolic Proteolysis: Calpains ""; ""2.3.2. Quality Control through Mitochondrial Proteolysis: Lon, Clp-Like, AAA-Proteases ""; ""2.3.3. Enzymatic Proteolysis Disruption in PD ""; ""3. THERAPEUTIC INTERVENTIONS BASED ON THE MODULATION OF CLEARANCE MECHANISMS ""; ""3.1. Proteasomal Clearance â€? A Target for Therapeutic Intervention ""; ""3.2. Autophagic Clearance â€? A Target for Therapeutic Intervention "" 
505 8 |a ""3.3. Proteases Clearance â€? A Target for Therapeutic Intervention """"CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES""; ""PARKINSONâ€?S DISEASE RELATED CHANGES OF OSCILLATORY ACTIVITY IN DISCRIMINATION TASKS ""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. METHODS ""; ""2.1. Experimental Procedure""; ""2.2. Analysis ""; ""3. EXPERIMENTAL RESULTS ""; ""Early (0â€?250 ms) Post-stimulus Interval ""; ""Late (250â€?600 ms) Post-stimulus Interval ""; ""4. DISCUSSION ""; ""CONCLUSION ""; ""REFERENCES "" 
505 8 |a ""NEW INSIGHTS INTO THE MECHANISM OF SLOWING OF VOLUNTARY MOVEMENTS IN PARKINSONâ€?S DISEASE """"ABSTRACT ""; ""ABBREVIATIONS ""; ""1. INTRODUCTION""; ""2. ANATOMIC ORGANIZATION OF THE BASAL GANGLIA ""; ""2.1. General Organization ""; ""2.2. Input and Output of Striatum and SNpc Connections ""; ""2.3. Input and Output of GP and SNpr, and STN Connections ""; ""2.4. Summary ""; ""3. PHYSIOLOGICAL FINDINGS OF THE BASAL GANGLIA IN ANIMALS ""; ""3.1. Neuronal Activity in Striatum, GPe and GPi ""; ""3.2. Neuronal Activity in STN, SNpc and SNpr "" 
505 8 |a ""3.3. Sequential Motor Actions and the Basal Ganglia""""3.4. Summary ""; ""4. CLINICAL SYMPTOMS OF PARKINSONâ€?S DISEASE ""; ""4.1. Slowness of Movement and Abnormal Movement Sequence ""; ""4.2. Impaired Synergy of Movement/Posture and Freezing, Loss of Postural Reflex and Festination""; ""4.3. Prolongation of Reaction Time ""; ""4.4. Reorganized Voluntary Eye Hand Coordinated Movement""; ""4.5. Impaired Time Perception and Reproduction ""; ""4.6. Summary ""; ""5. FUNCTIONAL CONSIDERATIONS OF SPATIO-TEMPORAL PROCESSING FOR MOVEMENT SYNERGY IN THE BASAL GANGLIA AND PARKINSONâ€?S DISEASE "" 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Parkinson's disease. 
650 0 |a Symptomatic Parkinson's disease. 
650 0 |a Brain  |x Diseases. 
650 2 |a Brain Diseases 
650 2 |a Parkinson Disease 
650 2 |a Parkinson Disease, Secondary 
650 6 |a Maladie de Parkinson. 
650 6 |a Cerveau  |x Maladies. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Alzheimer's & Dementia.  |2 bisacsh 
650 7 |a MEDICAL  |x Neurology.  |2 bisacsh 
650 7 |a Symptomatic Parkinson's disease  |2 fast 
650 7 |a Brain  |x Diseases  |2 fast 
650 7 |a Parkinson's disease  |2 fast 
700 1 |a Yoshida, Chiyo. 
700 1 |a Ito, Ami. 
776 0 8 |i Print version:  |z 9781619428300  |z 161942830X  |w (DLC) 2012470307 
830 0 |a Neurodegenerative diseases--laboratory and clinical research. 
856 4 0 |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=541059  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL3017811 
938 |a ebrary  |b EBRY  |n ebr10654782 
938 |a EBSCOhost  |b EBSC  |n 541059 
938 |a YBP Library Services  |b YANK  |n 7422447 
994 |a 92  |b IZTAP