Cargando…
The rheumatology handbook /
The Rheumatology Handbook is a unique resource for medical students and non-specialist doctors. It represents a collaborative effort between specialists from major teaching hospitals within the UK and Ireland, with each chapter being edited by a different consultant rheumatologist with the relevant...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Imperial College Press,
©2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Preface; Contributing Authors; Chapter 1 Basic Science for Rheumatology; 1.1. Introduction; 1.2. Anatomy of Bones and Joints; 1.2.1. Bones; Development of Bones; Microstructure; Macrostructure; Surface Features of Bones; Bone Turnover; Modulatory effectors of osteoblast function; Modulatory effectors of osteoclast function; 1.2.2. Joints; Classification and Function; Articular Surfaces; Cartilage; Fibrous Capsule; Synovial Membrane; Synovial Fluid; Ligaments; Intra-Articular Structures; Movement at Synovial Joints; 1.3. Biochemistry of Crystal Formation; 1.3.1. Sodium Urate Crystals.
- 1.3.2. Calcium Salt Crystals1.4. Innate and Adaptive Immunity; 1.4.1. Cells of the Innate Immune System; Neutrophils; Eosinophils; Basophils and Mast Cells; Monocytes and Macrophages; Natural Killer Cells; Dendritic Cells; 1.4.2. Soluble Factors in Innate Immunity; Complement Proteins; Acute Phase Proteins; 1.4.3. Cells of the Adaptive Immune System; T Cells; CD4 T cells; CD8 T cells; Regulatory T cells; B Cells; 1.4.4. Soluble Mediators of Adaptive Immunity; Antibodies; 1.4.5. Autoimmunity; Failure of Tolerance; Failure of central tolerance; Failure of peripheral tolerance.
- Hypersensitivity, Immunopathology and Autoimmunity1.5. Inflammation; 1.5.1. Angiogenesis; 1.5.2. Leukocyte Trafficking; 1.5.3. Cytokines and Chemokines; Cytokines; TNF- [alpha]; The IL-1 superfamily; The IL-6 family; The IL-17 family; Chemokines; Pleiotropy and Redundancy; 1.6. Genes and Proteins in Rheumatic Disease; 1.6.1. Deoxyribonucleic Acid and Protein; DNA; Genes, Transcription and Translation; 1.6.2. Genetic Disease; Monogenic and Polygenic Diseases; Genetics in Rheumatic Disease; Establishing heritability in polygenic disease; Identifying quantitive trait loci; Candidate gene analysis.
- HLA System and Predisposition to Rheumatic DiseasesThe Role of Abnormal Genes in the Pathogenesis of Disease; Chapter 2 Clinical Assessment of Patients with Rheumatic Disease; 2.1. Gait, Arms, Legs, Spine Screen; 2.2. History; Presenting Complaint; Past Medical History; Family History; Social History; Drug History; 2.3. Examination; 2.3.1. The Hand and Wrist; Pathology; Examination; Look; Feel; Move; Further examination; Special tests; 2.3.2. The Elbow; Pathology; Examination; Look; Feel; Move; Further examination; Special tests; 2.3.3. The Shoulder; Pathology; Examination; Look; Feel; Move.
- Further examinationSpecial tests; 2.3.4. The Hip; Pathology; Examination; Look; Feel; Move; Further examination; Special Tests; 2.3.5. The Knee; Pathology; Examination; Look; Feel; Move; Further examination; Special tests; 2.3.6. The Ankle and Foot; Pathology; Examination; Look; Feel; Move; Further examination; 2.3.7. The Neck; Pathology; Examination; Look; Feel; Move; Further examination; 2.3.8. The Thoracic and Lumbar Spine; Pathology; Examination; Look; Feel; Move; Further examination; Special tests; 2.3.9. Gait; 2.3.10. Extra-Articular Features of Rheumatic Disease.