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Tumor-suppressing viruses, genes, and drugs : innovative cancer therapy approaches /

Tumor Suppressing Viruses, Genes, and Drugs profiles the new generation of cancer treatments now in development. The book examines the innovative new approaches of viral, gene, and signal therapies that promise to replace or enhance conventional methods such as surgery, radiation, and chemotherapy....

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maruta, Hiroshi
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, ©2002.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Ch. 1. Oncolytic viruses: virotherapy for cancer
  • Ch. 2. Reovirus therapy of Ras-associated cancers
  • Ch. 3. Oncolytic herpes simplex virus (G207) therapy: from basic to clinical
  • Ch. 4. p53 and its targets
  • Ch. 5. Prospects for tumor suppressor gene therapy: RB as an example
  • Ch. 6. CDK inhibitors: genes and drugs
  • Ch. 7. CDK inhibitors: small molecular weight compounds
  • Ch. 8. NF1 and other RAS-binding peptides
  • Ch. 9. Cytoskeletal tumor suppressor genes
  • Ch. 10. TGF-[beta] signaling and carcinogenesis
  • Ch. 11. DAN gene
  • Ch. 12. Design of hammerhead ribozymes and allosterically controllable maxizymes for cancer gene therapy
  • Ch. 13. Inhibitors of angiogenesis
  • Ch. 14. Geranylgeranylated RhoB mediates the apoptotic and antineoplastic effects of farnesyltransferase inhibitors: new insights into cancer cell suicide
  • Ch. 15. RAS binding compounds
  • Ch. 16. Actin-binding drugs: MKT-007 and chaetoglobosin K (CK)
  • Ch. 17. Tyr kinase inhibitors as potential anticancer agents: EGF receptor and ABL kinases
  • Ch. 18. Antagonists of Rho family GTPases: blocking PAKs, ACKs, and rock
  • Ch. 19. Integrin antagonists as cancer therapeutics
  • Ch. 20. Functional rescue of mutant p53 as a strategy to combat cancer.