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Enzyme-mediated resistance to antibiotics : mechanisms, dissemination, and prospects for inhibition /

Antibiotic-resistant bacteria, or "superbugs," present an increasingly deadly threat to human health. With chapters from the world's leading researchers and scholars in this field, this comprehensive volume is a vital and timely overview of this critical subject.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bonomo, Robert A. (Editor ), Tolmasky, Marcelo (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : ASM Press, ©2007.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Enzyme-mediated resistance to antibiotics :  |b mechanisms, dissemination, and prospects for inhibition /  |c editors, Robert A. Bonomo, Marcelo Tolmasky. 
260 |a Washington, D.C. :  |b ASM Press,  |c ©2007. 
300 |a 1 online resource (xviii, 357 pages, 8 unnumbered pages of plates) :  |b illustrations (some color) 
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337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a data file  |2 rda 
504 |a Includes bibliographical references and index. 
505 0 |a Overview of aminoglycosides and enzyme-mediated bacterial resistance: clinical implications / Robert A. Bonomo -- Aminoglycoside antibiotics / Kanchana Majumder [and others] -- Structural aspects of aminoglycoside-modifying enzymes / Gerard D. Wright and Albert M. Berghuis -- Aminoglycoside-modifying enzymes: characteristics, localization, and dissemination / Marcelo E. Tolmasky -- rRNA methylases and resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone (MLSKO) antibiotics / Marilyn C. Roberts -- [Beta]-lactamases: historical perspectives / Karen Bush and Patricia A. Bradford -- Resistance mediated by penicillin-binding proteins / Malcolm G.P. Page -- Inhibition of class A [beta]-lactamases / Samy O. Meroueh, Jooyoung Cha, And Shahriar Mobashery -- Class B [beta]-lactamases / Gian Maria Rossolini and Jean-Denis Docquier -- Crystal structures of class C [beta]-lactamases: mechanistic implications and perspectives in drug design / C. Bauvois and J. Wouters. 
505 0 |a Class D [beta]-lactamases / Franck Danel, Malcolm G.P. Page, and David M. Livermore -- Kinetics of [beta]-lactamases and penicillin-binding proteins / Moreno Galleni and Jean-Marie Frère -- The pharmaceutical industry and inhibitors of bacterial enzymes: implications for drug development / David M. Shlaes, Lefa Alksne, and Steven J. Projan -- [Beta]-lactamase inhibitory proteins / Zhen Zhang and Timothy Palzkill -- Active drug efflux in bacteria / Jürg Dreier -- Overview of dissemination mechanisms of genes coding for resistance to antibiotics / Marcelo E. Tolmasky -- Conjugative transposons / Louis B. Rice -- The dissemination of antibiotic resistance by bacterial conjugation / Virginia L. Waters -- Bacterial toxin-antitoxin systems as targets for the development of novel antibiotics / Juan C. Alonso [and others] -- Integrons and superintegrons / Robert A. Bonomo, Andrea M. Hujer, and Kristine M. Hujer -- The biological cost of antibiotic resistance / Dan I. Andersson [and others]. 
588 0 |a Print version record. 
520 |a Antibiotic-resistant bacteria, or "superbugs," present an increasingly deadly threat to human health. With chapters from the world's leading researchers and scholars in this field, this comprehensive volume is a vital and timely overview of this critical subject. 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Drug resistance in microorganisms. 
650 0 |a Drug resistance in microorganisms  |x Genetic aspects. 
650 0 |a Microbial enzymes. 
650 0 |a Enzyme inhibitors. 
650 1 2 |a Anti-Bacterial Agents 
650 1 2 |a Drug Resistance, Bacterial 
650 2 2 |a Enzyme Inhibitors 
650 2 2 |a beta-Lactamase Inhibitors 
650 6 |a Enzymes microbiennes. 
650 6 |a Bactéries pathogènes  |x Résistance aux médicaments. 
650 6 |a Antienzymes. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Enzyme inhibitors.  |2 fast  |0 (OCoLC)fst00913597 
650 7 |a Drug resistance in microorganisms.  |2 fast  |0 (OCoLC)fst00898704 
650 7 |a Drug resistance in microorganisms  |x Genetic aspects.  |2 fast  |0 (OCoLC)fst00898705 
650 7 |a Microbial enzymes.  |2 fast  |0 (OCoLC)fst01019490 
700 1 |a Bonomo, Robert A.,  |e editor. 
700 1 |a Tolmasky, Marcelo,  |e editor. 
776 0 8 |i Print version:  |t Enzyme-mediated resistance to antibiotics.  |d Washington, D.C. : ASM Press, ©2007  |z 9781555813031  |w (DLC) 2007002039  |w (OCoLC)80019936 
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