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MicroRNAs : from basic science to disease biology /
MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluatio...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge ; New York :
Cambridge University Press,
2008.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a MicroRNAs : |b from basic science to disease biology / |c edited by Krishnarao Appasani ; forewords by Victor R. Ambros and Sidney Altman. |
| 260 | |a Cambridge ; |a New York : |b Cambridge University Press, |c 2008. | ||
| 300 | |a 1 online resource (xxviii, 531 pages, 20 unnumbered pages of plates) : |b illustrations (some color) | ||
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| 504 | |a Includes bibliographical references and index. | ||
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| 505 | 0 | |a Discovery of microRNAs in various organisms -- MicroRNAs functions and RNAi-mediated pathways -- Computational biology of microRNAs -- Detection and quantitation of microRNAs -- MicroRNAs in disease biology -- MicroRNAs in stem cell development. | |
| 520 | |a MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging 2007 reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R & D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. | ||
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