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MicroRNAs : from basic science to disease biology /

MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluatio...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Appasani, Krishnarao, 1959-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge ; New York : Cambridge University Press, 2008.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their discovery has revolutionised both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging 2007 reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R & D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.
Descripción Física:1 online resource (xxviii, 531 pages, 20 unnumbered pages of plates) : illustrations (some color)
Bibliografía:Includes bibliographical references and index.
ISBN:9780511457180
0511457189
0511541767
9780511541766