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Statistical aspects of the design and analysis of clinical trials /

About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. In this book, the statis...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Everitt, Brian
Otros Autores: Pickles, Andrew
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : River Edge, NJ : Imperial College Press ; Distributed by World Scientific Pub. Co., ©1999.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • An introduction to clinical trials
  • Treatment allocation, the size of trials and reporting results
  • Monitoring trial progress: outcome measures, compliance, dropouts and interim analyses
  • Basic analyses of clinical trials, the generalized linear model and the economic evaluation of trials
  • Simple approaches to the analysis of longitudinal data from clinical trials
  • Multivariate normal regression models for longitudinal data from clinical trials
  • Models for non-normal longitudinal data from clinical trials
  • Survival analysis
  • Bayesian methods
  • Meta-analysis.