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Berek and Hacker's Gynecologic Oncology
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Philadelphia :
Wolters Kluwer Health,
2020.
|
| Edición: | 7th ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover
- Title Page
- Copyright
- Dedication
- Contributors
- Foreword to the First Edition
- Preface
- Contents
- Section I: General Principles
- Chapter 1: Cancer Genetics
- Historic Perspective
- Genetic Changes
- Sporadic
- Hereditary
- Oncogenes
- Types of Oncogenes
- Tumor Suppressor Genes (Anti-Oncogenes)
- Epigenetic Changes
- Genetic Changes in Gynecologic Malignancies
- Endometrial Cancer
- Uterine Mesenchymal Tumors
- Ovarian Cancer
- Ovarian Sex Cord Stromal Tumors
- Cervical Cancer
- Vulvar Cancer
- Gestational Trophoblastic Disease
- Chapter 2: Cancer Cell Biology
- Cell Growth and Proliferation
- Oncogenes
- Tumor Suppressor Genes
- DNA Repair
- DNA Damage Response Defects and Synthetic Lethality to Enhance Efficacy of Cancer Therapy
- Cell Death Pathways
- Autophagy
- Apoptosis
- Necrosis
- Cancer Stem Cells
- Cellular Senescence
- Cell Metabolism
- Hormone Metabolism
- Post-translational Modifications
- Cell Invasion and Metastasis
- Epithelial-to-Mesenchymal Transition
- Tumor Microenvironment
- Immune Checkpoints
- Angiogenesis
- Biomarkers
- Tumor Markers
- Chapter 3: Biologic, Targeted, and Immune Therapy
- Inhibitors of Growth Factor Receptors
- EGFR Inhibitors
- EGFR Inhibitors-Small Molecules
- EGFR Inhibitors-Monoclonal Antibodies
- Her2/Neu Inhibitors
- Her2/Neu Inhibitors-Small Molecules
- Her2/Neu Inhibitors-Monoclonal Antibodies
- PDGFR Inhibitors-Monoclonal Antibodies
- Inhibitors of Angiogenesis
- VEGFR Inhibitors-Small Molecules
- VEGFR Inhibitors-Monoclonal Antibodies
- Inhibitors of Other Intracellular Kinases
- Small Molecules
- Braf (Rapidly Activated Fibrosarcoma) Inhibitors
- MEK1-2 (MAPK/ERK Kinase) Inhibitors
- CDK 4-6 (Cyclin-Dependent Kinases 4-6) Inhibitors
- ALK (Anaplastic Lymphoma Kinase) Inhibitors
- PI-3K (Phosphatidylinositol 3-Kinase) Inhibitors
- mTOR (Mammalian Target of Rapamycin) Inhibitors
- Inhibitors of DNA Repair
- PARP (Poly-ADP Ribose-Polymerase) Inhibitors
- Immunotherapy
- Cytokines
- Monoclonal Antibodies
- Immune Checkpoint Inhibitors
- Anti-PD-1 (Programmed Cell Death Receptor-1) Antibodies
- Anti-PD-L1 (Programmed Cell Death Receptor Ligand-1) Antibodies
- Therapeutic Cancer Vaccines
- Cell-Based Vaccines
- Glycan-Based Vaccines
- Adoptive Cell Therapy
- Chapter 4: Chemotherapy
- General Principles
- Tumor Growth and Chemotherapy
- Differential Sensitivity
- Therapeutic Index
- Brief History of Chemotherapy
- Biologic Factors Influencing Treatment
- Cell Kinetic Concepts
- Cancer Cell Growth
- Principles of Chemotherapy
- Neoadjuvant Chemotherapy
- Hyperthermic Intraperitoneal Chemotherapy
- Antibody-Drug Conjugates
- Chemotherapy in Pregnancy
- Drug Resistance
- Excretion
- Drug Interactions
- Combination Chemotherapy
- Clinical Benefit
- RECIST Criteria
- Dose Adjustment
- Carboplatin Dose Calculation