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|a 1184240272
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|a 9781119432494
|b Wiley
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|a RC271.R3
|b .P743 2021
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|a 616.9940642
|2 23
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|a UAMI
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|a Precision Medicine in Oncology /
|c Bulent Aydogan, James A. Radosevich.
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| 250 |
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|a 1st.
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| 264 |
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|b Wiley-Blackwell,
|c 2020.
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| 300 |
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|a 1 online resource (288 pages)
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| 336 |
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|a text
|2 rdacontent
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| 337 |
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|a computer
|2 rdamedia
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| 338 |
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|a online resource
|2 rdacarrier
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| 500 |
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|a List of Contributors Preface List of Abbreviations Chapter 1 Genomic Strategies for Personalized Cancer Therapy Chapter 2 Blood-based biomarkers for the diagnosis and prognosis of cancer Chapter 3 Application of circulating cell free DNA for personalized cancer therapy Chapter 4 Prognostic Implications of EGFR, p53, p16, cyclin D1, Bcl-2 in Head & Neck Squamous Cell Carcinoma (HNSCC) Chapter 6 Predictive and prognostic markers for cancer medicine Chapter 7 Dual Energy Imaging in Precision Radiation Therapy Chapter 8 The role of Big Data in personalized medicine.
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| 506 |
1 |
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|a Legal Deposit;
|c Only available on premises controlled by the deposit library and to one user at any one time;
|e The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
|5 WlAbNL
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| 540 |
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|a Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.
|5 WlAbNL
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|a Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- List of Abbreviations -- Chapter 1 Genomic Strategies for Personalized Cancer Therapy -- 1.1 Introduction -- 1.1.1 Definition of Precision Medicine in Oncology -- 1.1.2 DNA and RNA Sequencing Techniques -- 1.2 Precision Medicine in Specific Tumors -- 1.2.1 Lung Cancer -- 1.2.1.1 Adenocarcinoma -- 1.2.1.2 Squamous Cell Carcinoma -- 1.2.1.3 Small-Cell Lung Carcinoma (SCLC) -- 1.2.1.4 Epidermal Growth Factor Receptor (EGFR) Mutations -- 1.2.1.5 Anaplastic Lymphoma Kinase (ALK) -- 1.2.1.6 BRAF, ROS1, MET
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|a 1.2.1.7 KRAS -- 1.2.1.8 Other: RET, NTRK -- 1.2.2 Head and Neck Cancers -- 1.2.2.1 HPV-Positive Cancers -- 1.2.2.2 HPV-Negative Cancers -- 1.2.2.3 Targeting the Epidermal Growth Factor Receptor (EGFR) Pathway -- 1.2.2.4 Thyroid Cancers -- 1.2.2.5 Other Targets -- 1.2.3 Hematological Malignancies -- 1.2.3.1 Lymphoma -- 1.2.3.2 Leukemia -- 1.2.3.3 Myelodysplastic Syndrome -- 1.2.4 Gynecologic Malignancies -- 1.2.4.1 Cervical -- 1.2.4.2 Uterine -- 1.2.4.3 Ovarian -- 1.2.5 Melanoma -- 1.2.6 Gastrointestinal Malignancies -- 1.2.6.1 Gastroesophageal Cancers -- 1.2.6.2 Colorectal Cancers
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|a 1.2.7 Breast Cancer -- 1.2.7.1 Basal-Like, or Triple Negative Breast Cancer -- 1.2.7.2 Luminal A/B, or Hormone Positive -- 1.2.7.3 HER2 Positive Breast Cancer -- 1.2.7.4 Immunotherapy -- 1.2.7.5 Germline Testing in Breast Cancer -- 1.2.7.6 Conclusion -- 1.2.8 Genitourinary Malignancies -- 1.2.8.1 Prostate Cancer -- 1.2.8.2 Renal Cell Cancer (RCC) -- 1.2.8.3 Urothelial Cancers -- 1.2.9 Pediatric Cancers -- 1.2.9.1 Introduction -- 1.2.9.2 Leukemia and Lymphoma -- 1.2.9.3 Central and Peripheral Nervous System Tumors -- 1.2.9.4 Bone and Soft Tissue Sarcomas -- 1.2.9.5 Other Embryonal Tumors
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|a 1.2.9.6 Conclusion -- 1.2.10 Cancers of Unknown Primary Origin -- 1.2.10.1 Diagnosis -- 1.2.10.2 Gene Expression Profiling -- 1.2.10.3 Mutational Testing with Next-Generation Sequencing (NGS) -- 1.2.10.4 Treatment -- 1.3 Biomarkers for Immunotherapy of Cancer -- 1.3.1 PD-L1 -- 1.3.2 Soluble PD-L1 (sPD-L1) -- 1.3.3 Combined Positive Score (CPS) -- 1.3.4 Tumor Microenvironment -- 1.3.5 Tumor Mutational Burden (TMB) -- 1.3.6 Microsatellite Instability (MSI) -- 1.3.7 MMR Deficiency -- 1.3.8 Peripheral Blood Absolute Neutrophil Count/Absolute Lymphocyte Count -- 1.3.9 Microbiome
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|a 1.4 Clinical Trial Design in the Era of Precision Oncology -- 1.5 Ethical, Legal, and Social Issues of Precision Oncology -- 1.5.1 Ethical Issues -- 1.5.2 Legal Issues -- 1.5.3 Social Issues -- 1.6 Databases, Data Sharing, and Challenges of Precision Oncology -- References -- Chapter 2 Blood-Based Biomarkers for the Diagnosis and Prognosis of Cancer -- 2.3 Circulating Proteins as Biomarkers -- 2.4 Circulating Long Non-coding RNAs as Biomarkers -- 2.5 Circulating miRNAs as Biomarkers -- 2.6 Circulating Autoantibodies as Biomarkers -- 2.7 Circulating Tumor DNA as Biomarkers
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| 590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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| 650 |
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|a Cancer
|x Radiotherapy.
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| 650 |
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2 |
|a Radiation Oncology
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| 650 |
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6 |
|a Cancer
|x Radiothérapie.
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| 650 |
|
7 |
|a Cancer
|x Radiotherapy
|2 fast
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| 700 |
1 |
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|a Aydogan, Bulent,
|e editor.
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| 700 |
1 |
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|a Radosevich, James A.,
|e editor.
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| 758 |
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|i has work:
|a Precision medicine in oncology (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGCgj7tt7KjXgdmbXcPc8y
|4 https://id.oclc.org/worldcat/ontology/hasWork
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| 776 |
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|i Print version:
|a Radosevich, James A.
|t Precision Medicine in Oncology
|d Newark : John Wiley & Sons, Incorporated,c2020
|z 9781119432449
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