Translational nanomedicine /
"The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics."--
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Weinheim, Germany :
Wiley-VCH Verlag GmbH & Co. KGaA,
[2020]
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Colección: | Advances in molecular biology and medicine.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Part I Laboratory Techniques
- Chapter 1 Microfluidics in Nanomedicine
- 1 Introduction
- 1.1 Nanomedicine Development
- 1.2 Microfluidics Technology
- 2 Microfluidic Assembly of Nanomedicines
- 3 Microfluidic Characterization of Nanomedicines
- 4 Microfluidic Evaluation of Nanomedicines
- 4.1 Mimicking Physiological Environments
- 4.2 Endothelial Cell Systems
- 4.3 "Organ-On-A-Chip"
- 4.4 Renal Toxicity and Hepatotoxicity
- 4.5 Live Tissue Explants
- 5 Challenges and Opportunities
- 6 Concluding Remarks
- Acknowledgments
- References
- Chapter 2 Quantum Dots for Biomedical Delivery Applications
- 1 Introduction
- 2 Properties of QDs
- 3 Lithographically Defined QDs
- 4 Colloidal QDs
- 5 QDs Application in Optics
- 6 Transport (Electrical) Properties of QDs
- 7 Application of QDs in Diagnostics
- 8 Nucleic Acid Detection
- 9 Application of QDs in Drug Treatments
- Acknowledgments
- References
- Part II Devices
- Chapter 3 DNA Origami Nanorobots
- 1 Introduction to Robotics
- 1.1 A Brief History of Robotics
- 1.2 Robotic Control of Molecules
- 2 DNA Nanotechnology
- 2.1 Computing
- 2.2 Nanofabrication
- 2.3 Nucleic Acid Enzymes
- 2.4 Nucleic Acid Sensors
- 2.5 DNA Actuators and Motors
- 2.6 Miscellaneous Functions of Nucleic Acids
- 2.7 DNA Origami
- 2.8 Computer-Aided Design (CAD) Tools for DNA Nanostructures
- 2.9 Designing Scaffolded Origami in caDNAno: A Guided Tour
- 3 DNA Nanorobotics
- 3.1 Case Study: A DNA Nanorobot
- 3.2 Sensing the Environment
- 3.3 Information Processing and Logic Types
- 3.4 Collective Behaviors
- 3.5 Synthetic Genetic Circuits and DNA Nanorobotics
- 4 Challenges of Applying DNA Nanorobots to Therapeutics
- 5 Summary and Conclusions
- References
- Chapter 4 Graphene and Graphene Derivatives in Biosensing, Imaging, Therapeutics, and Genetic Engineering
- 1 Introduction
- 2 Biosensing
- 2.1 Modification of Bioreceptor on Graphene by Covalent and Noncovalent Interactions
- 2.2 Advantage of Graphene/Nanoparticle Hybrids in Enhancing Transducer Performance
- 3 Bioimaging
- 3.1 Optical Imaging: NIR Imaging, Fluorescence, Multiphoton Excitation Imaging
- 3.1.1 NIR Imaging
- 3.1.2 Fluorescence Imaging
- 3.1.3 Multiphoton Excitation Imaging
- 3.2 Localized Surface Plasmon Resonance (LSPR)
- 3.3 Raman Imaging
- 3.4 Magnetic Resonance Imaging (MRI)
- 3.5 Positron Emission Tomography (PET)
- 4 Therapeutics
- 4.1 Drug Loading by Noncovalent Interactions
- 4.2 Drug Loading by Host-Guest Interaction
- 4.3 Controlled Release System
- 4.4 Photodynamic and Photothermal Therapy
- 4.5 Combination of Diagnostics and Therapeutics: Graphene-Based Theranostics System
- 5 Genetic Engineering
- 6 Conclusions
- Acknowledgments
- References
- Chapter 5 Synthetic Gene Circuits
- 1 Introduction to Synthetic Gene Circuits
- 2 Building Blocks of Synthetic Gene Circuits