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Translational nanomedicine /

"The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics."--

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Meyers, Robert A. (Robert Allen), 1936- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Weinheim, Germany : Wiley-VCH Verlag GmbH & Co. KGaA, [2020]
Colección:Advances in molecular biology and medicine.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Part I Laboratory Techniques
  • Chapter 1 Microfluidics in Nanomedicine
  • 1 Introduction
  • 1.1 Nanomedicine Development
  • 1.2 Microfluidics Technology
  • 2 Microfluidic Assembly of Nanomedicines
  • 3 Microfluidic Characterization of Nanomedicines
  • 4 Microfluidic Evaluation of Nanomedicines
  • 4.1 Mimicking Physiological Environments
  • 4.2 Endothelial Cell Systems
  • 4.3 "Organ-On-A-Chip"
  • 4.4 Renal Toxicity and Hepatotoxicity
  • 4.5 Live Tissue Explants
  • 5 Challenges and Opportunities
  • 6 Concluding Remarks
  • Acknowledgments
  • References
  • Chapter 2 Quantum Dots for Biomedical Delivery Applications
  • 1 Introduction
  • 2 Properties of QDs
  • 3 Lithographically Defined QDs
  • 4 Colloidal QDs
  • 5 QDs Application in Optics
  • 6 Transport (Electrical) Properties of QDs
  • 7 Application of QDs in Diagnostics
  • 8 Nucleic Acid Detection
  • 9 Application of QDs in Drug Treatments
  • Acknowledgments
  • References
  • Part II Devices
  • Chapter 3 DNA Origami Nanorobots
  • 1 Introduction to Robotics
  • 1.1 A Brief History of Robotics
  • 1.2 Robotic Control of Molecules
  • 2 DNA Nanotechnology
  • 2.1 Computing
  • 2.2 Nanofabrication
  • 2.3 Nucleic Acid Enzymes
  • 2.4 Nucleic Acid Sensors
  • 2.5 DNA Actuators and Motors
  • 2.6 Miscellaneous Functions of Nucleic Acids
  • 2.7 DNA Origami
  • 2.8 Computer-Aided Design (CAD) Tools for DNA Nanostructures
  • 2.9 Designing Scaffolded Origami in caDNAno: A Guided Tour
  • 3 DNA Nanorobotics
  • 3.1 Case Study: A DNA Nanorobot
  • 3.2 Sensing the Environment
  • 3.3 Information Processing and Logic Types
  • 3.4 Collective Behaviors
  • 3.5 Synthetic Genetic Circuits and DNA Nanorobotics
  • 4 Challenges of Applying DNA Nanorobots to Therapeutics
  • 5 Summary and Conclusions
  • References
  • Chapter 4 Graphene and Graphene Derivatives in Biosensing, Imaging, Therapeutics, and Genetic Engineering
  • 1 Introduction
  • 2 Biosensing
  • 2.1 Modification of Bioreceptor on Graphene by Covalent and Noncovalent Interactions
  • 2.2 Advantage of Graphene/Nanoparticle Hybrids in Enhancing Transducer Performance
  • 3 Bioimaging
  • 3.1 Optical Imaging: NIR Imaging, Fluorescence, Multiphoton Excitation Imaging
  • 3.1.1 NIR Imaging
  • 3.1.2 Fluorescence Imaging
  • 3.1.3 Multiphoton Excitation Imaging
  • 3.2 Localized Surface Plasmon Resonance (LSPR)
  • 3.3 Raman Imaging
  • 3.4 Magnetic Resonance Imaging (MRI)
  • 3.5 Positron Emission Tomography (PET)
  • 4 Therapeutics
  • 4.1 Drug Loading by Noncovalent Interactions
  • 4.2 Drug Loading by Host-Guest Interaction
  • 4.3 Controlled Release System
  • 4.4 Photodynamic and Photothermal Therapy
  • 4.5 Combination of Diagnostics and Therapeutics: Graphene-Based Theranostics System
  • 5 Genetic Engineering
  • 6 Conclusions
  • Acknowledgments
  • References
  • Chapter 5 Synthetic Gene Circuits
  • 1 Introduction to Synthetic Gene Circuits
  • 2 Building Blocks of Synthetic Gene Circuits