Cargando…

SUMOylation and ubiquitination : current and emerging concepts /

Most proteins undergo post-translational modifications altering physical and chemical properties, folding, conformation distribution, stability, activity and function. Ubiquitin and SUMOs are related small proteins that are members of the large ubiquitin superfamily of post-translational modifiers....

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Wilson, Van Gene (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Norfolk, UK : Caister Academic Press, 2019.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000 i 4500
001 EBOOKCENTRAL_on1119527833
003 OCoLC
005 20240329122006.0
006 m o d
007 cr |||||||||||
008 190912s2019 enk ob 001 0 eng d
040 |a HUA  |b eng  |e rda  |e pn  |c HUA  |d N$T  |d EBLCP  |d OCLCF  |d OCLCQ  |d UKAHL  |d OCLCQ  |d OCLCO  |d K6U  |d OCLCQ  |d OCLCO  |d OCLCL 
020 |a 9781912530137  |q (electronic bk.) 
020 |a 1912530139  |q (electronic bk.) 
020 |z 9781912530120 
029 1 |a AU@  |b 000071301176 
035 |a (OCoLC)1119527833 
050 4 |a QP552.U24 
082 0 4 |a 572.6  |2 23 
049 |a UAMI 
245 0 0 |a SUMOylation and ubiquitination :  |b current and emerging concepts /  |c edited by Van G. Wilson, Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A & M University, Bryan, TX, USA. 
264 1 |a Norfolk, UK :  |b Caister Academic Press,  |c 2019. 
300 |a 1 online resource (viii, 503 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
520 |a Most proteins undergo post-translational modifications altering physical and chemical properties, folding, conformation distribution, stability, activity and function. Ubiquitin and SUMOs are related small proteins that are members of the large ubiquitin superfamily of post-translational modifiers. Written by highly respected leaders in their fields under the expert guidance of the editor, this volume covers the principles of ubiquitination and SUMOylation, presents detailed reviews of current and emerging concepts and highlights new advances in all areas of SUMOylation and ubiquitination. Topics of note include: the ubiquitin superfamily, the ubiquitin toolbox, onco viral exploitation of the SUMO system, small molecule modulators of desumoylation, mass spectrometry, global proteomic profiling of SUMO and ubiquitin, biotin-based approaches, genetic screening, SUMOylation networks in humans, targets for ubiquitin ligases, regulation of p53, protein homeostasis, miRNAs, DNA replication, DNA damage response, telomere biology, intracellular trafficking, regulation of angiogenesis, brain ischemia, autophagy, assembly and activity, antiviral defense, HIV infection, amyloid and amyloid-like proteins, plant immunity. This comprehensive and up-to-date book is the definitive reference volume on all aspects of SUMOylation and ubiquitination and is an essential acquisition for anyone involved in this area of biology. 
588 0 |a On-line resource; title from PDF title page (EBSCO, viewed September 16, 2019) 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Ubiquitin. 
650 0 |a Post-translational modification. 
650 2 |a Ubiquitins 
650 6 |a Ubiquitine. 
650 6 |a Protéines  |x Modification post-traductionnelle. 
650 7 |a Post-translational modification  |2 fast 
650 7 |a Ubiquitin  |2 fast 
700 1 |a Wilson, Van Gene,  |e editor. 
758 |i has work:  |a SUMOylation and ubiquitination (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCH8V8rygkVX6C7PqMqCyBd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t SUMOylation and ubiquitination.  |d Norfolk, UK : Caister academic press, 2019  |z 9781912530120  |w (OCoLC)1099270795 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5897812  |z Texto completo 
938 |a Askews and Holts Library Services  |b ASKH  |n AH36303272 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL5897812 
938 |a EBSCOhost  |b EBSC  |n 2236773 
994 |a 92  |b IZTAP