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Mass spectrometry : an applied approach.

Provides a comprehensive description of mass spectrometry basics, applications, and perspectivesMass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, co...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Smoluch, Marek, 1977- (Editor ), Grasso, Giuseppe, 1974- (Editor ), Suder, Piotr, 1949- (Editor ), Silberring, Jerzy, 1949- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, NJ : Wiley, 2019.
Edición:Second edition /
Colección:Wiley-Interscience series on mass spectrometry.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Mass spectrometry :  |b an applied approach. 
250 |a Second edition /  |b edited by Marek Smoluch, Giuseppe Grasso, Piotr Suder, and Jerzy Silberring. 
264 1 |a Hoboken, NJ :  |b Wiley,  |c 2019. 
300 |a 1 online resource (xxi, 418 pages) 
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490 1 |a Wiley Series on Mass Spectrometry ; 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from digital title page (viewed on August 06, 2019). 
520 |a Provides a comprehensive description of mass spectrometry basics, applications, and perspectivesMass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry--from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule. 
505 0 |a Atmospheric pressure ionization (API) IV.1.3.01 Atmospheric pressure chemical ionization (APCI) IV.1.3.02 Electrospray (ESI) IV.1.3.02.1 Introduction IV.1.3.02.2 ESI principle of operation IV.1.3.02.3 ESI - working principles IV.1.3.02.4 Properties of the solvent IV.1.3.02.5 Principles of ESI-MS spectra interpretation IV.1.3.03 Nanoelectrospray (nanoESI) IV.1.3.03.1 Introduction IV.1.3.03.2 Nanospray sensitivity IV.1.3.03.3 Ionization in nanoelectrospray and electrospray ion sources IV.1.3.03.4 Off-line nanospray and practical advices IV.1.3.03.5 On-line nanospray and practical advices IV.1.3.03.6 Summary IV.1.3.04 Desorption electrospray ionization (DESI) IV.1.3.04.1 Introduction IV.1.3.04.2 Construction of the ion source IV.1.3.04.3 Principles of operation IV.1.3.04.4 Mechanism of ions formation IV.1.3.04.5 The role of surface for sample 
505 0 |a IV.1.7.03 The sputtering of the sample surface IV.1.7.04 Ionization (generating secondary ions) IV.1.7.05 Construction of TOF-SIMS IV.1.7.06 Analytical capabilities of TOF-SIMS IV.1.7.06.1 Static TOF-SIMS IV.1.7.06.2 Visualization of sample surface IV.1.7.06.3 Dynamic SIMS - in-depth analysis IV.1.7.07 Examples and spectra interpretation IV.1.7.07.1 Speciation analysis IV.1.7.07.2 Distribution of species on the surface IV.1.7.07.3 In-depth speciation analysis IV.2 Analyzers IV.2.1. Time-of-Flight (TOF) IV.2.1.01 Introduction IV.2.1.02 The working rule of TOF analyzer IV.2.1.03 Linear mode of operation of TOF IV.2.1.04 The spread of the kinetic energy regarding the ions of the same mass IV.2.1.05 Delayed ion extraction IV.2.1.06 The reflection mode IV.2.1.07 Orthogonal acceleration IV.2.1.08 Summary IV.2.2. 
505 0 |a Ion mobility analyzer (IM) IV.2.2.01 Principle of IM operation IV.2.2.02 Drift time IMS IV.2.2.03 FAIMS (high-field asymmetric waveform ion mobility spectrometer) IV.2.2.04 TWIG (travelling wave ion guides) IV.2.2.05 IM spectrum IV.2.2.06 Applications IV.2.3 Quadrupole mass analyzer (Q) IV.2.3.01 Construction and principles of operation of a quadrupole IV.2.3.02 Behavior of an ion inside the quadrupole IV.2.3.03 How mass spectrum is generated? Changes of U and V IV.2.3.04 Spectrum quality IV.2.3.05 Applications of the quadrupole analyzer IV.2.3.06 Quadrupoles, hexapoles and octapoles as focusing elements -- ion guides IV.2.4. 
505 0 |a Ion trap (IT) IV.2.4.01 Introduction IV.2.4.02 Behavior of an ion inside the ion trap IV.2.4.03 Analysis of the ions IV.2.4.04 Tandem in space Mass Selective Instability Mode IV.2.4.05 Resonant Ejection Mode IV.2.4.06 Axial Modulation IV.2.4.07 Nonlinear Resonance IV.2.4.08 Linear ion trap LIT IV.2.4.09 Applications IV.2.5. High resolution mass spectrometry IV.2.5.01 Introduction IV.2.6. Ion cyclotron resonance (ICR) IV.2.6.01 Introduction IV.2.6.02 Cyclotron frequency IV.2.6.03 ICR -- principles of operation IV.2.6.04 Injection of ions into the ICR cell IV.2.6.05 Trapping electrodes IV.2.6.06 Excitation electrodes IV.2.6.07 Detection electrodes and Fourier transform IV.2.6.08 FT-ICR properties as m/z analyzer IV.2.7. 
505 0 |a Hyphenated techniques V.1. Gas chromatography combined with mass spectrometry GC-MS V.1.1. Introduction V.1.2 Detectors V.1.3. Chemical modifications - derivatization V.1.4. GC-MS analysis V.1.5. Two-dimensional gas chromatography linked to mass spectrometry 2D GC-MS V.2. Liquid chromatography linked to mass spectrometry (LC-MS) V.2.1. Introduction V.2.2. Introduction to liquid chromatography V.2.3. Types of detectors V.2.4. Chromatographic columns V.2.5. Chromatographic separation and quantitation using MS as a detector V.2.6. Construction of an interface linking liquid chromatograph to the mass spectrometer V.2.6.01 Introduction V.2.6.02 ESI interface V.2.6.03 APCI connection to MS V.2.6.04 APPI inte 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Mass spectrometry. 
650 0 |a Spectrum analysis. 
650 2 |a Mass Spectrometry 
650 6 |a Spectrométrie de masse. 
650 7 |a mass spectrometry.  |2 aat 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Mass spectrometry  |2 fast 
650 7 |a Spectrum analysis  |2 fast 
650 7 |0 (FrPBN)11944584  |a Spectroscopie de masse.  |2 ram 
700 1 |a Smoluch, Marek,  |d 1977-  |e editor. 
700 1 |a Grasso, Giuseppe,  |d 1974-  |e editor. 
700 1 |a Suder, Piotr,  |d 1949-  |e editor. 
700 1 |a Silberring, Jerzy,  |d 1949-  |e editor. 
776 0 8 |i Print version:  |t Mass spectrometry.  |b Second edition / edited by Marek Smoluch, Giuseppe Grasso, Piotr Suder, Jerzy Silberring.  |d Hoboken, NJ : Wiley, 2019  |z 9781119377306  |w (DLC) 2019011643 
830 0 |a Wiley-Interscience series on mass spectrometry. 
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