Cargando…

Bioprocessing technology for production of biopharmaceuticals and bioproducts /

"Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: Summarize...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Komives, Claire (Editor ), Zhou, Weichang, 1963- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, NJ : John Wiley & Sons, Inc., 2019.
Edición:First edition.
Colección:Wiley series in biotechnology and bioengineering.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000 i 4500
001 EBOOKCENTRAL_on1048055848
003 OCoLC
005 20240329122006.0
006 m o d
007 cr |||||||||||
008 180804s2019 nju ob 001 0 eng
010 |a  2018037472 
040 |a DLC  |b eng  |e rda  |c DLC  |d OCLCO  |d OCLCQ  |d OCLCA  |d EBLCP  |d N$T  |d DG1  |d STF  |d OCLCO  |d CHVBK  |d OCLCF  |d OCLCO  |d YDX  |d OCLCO  |d UAB  |d OCLCO  |d AU@  |d OCLCQ  |d OCLCO  |d OCLCA  |d OCLCQ  |d OCLCA  |d OCLCQ  |d OCLCA  |d OCLCO  |d OCLCQ  |d OCL  |d OCLCO  |d OCLCQ  |d OCLCL 
019 |a 1079363250 
020 |a 9781119378280  |q (Adobe PDF) 
020 |a 1119378281  |q (Adobe PDF) 
020 |a 9781119378303  |q (ePub) 
020 |a 1119378303  |q (ePub) 
020 |a 9781119378341  |q (electronic bk.) 
020 |a 1119378346  |q (electronic bk.) 
020 |z 9781118361986  |q (hardback) 
029 1 |a AU@  |b 000063820645 
029 1 |a CHNEW  |b 001030741 
029 1 |a CHVBK  |b 551943491 
029 1 |a GBVCP  |b 1048686868 
035 |a (OCoLC)1048055848  |z (OCoLC)1079363250 
042 |a pcc 
050 1 0 |a RM301.25  |b .B56 2019 
060 1 0 |a QV 241  |b .B615 2019 
072 7 |a MED  |x 071000  |2 bisacsh 
082 0 0 |a 615.1/9  |2 23 
049 |a UAMI 
245 0 0 |a Bioprocessing technology for production of biopharmaceuticals and bioproducts /  |c edited by Claire Komives, Weichang Zhou. 
250 |a First edition. 
264 1 |a Hoboken, NJ :  |b John Wiley & Sons, Inc.,  |c 2019. 
300 |a 1 online resource (xiii, 273). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Wiley series in biotechnology and bioengineering 
504 |a Includes bibliographical references and index. 
520 |a "Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries Includes illustrative case studies that review six milestone bio-products Discusses a wide selection of host strain types and disruptive bioprocess technologies"--Provided by publisher 
588 0 |a Print version record and CIP data provided by publisher; resource not viewed. 
505 0 |a Cover; Title Page; Copyright; Contents; List of Contributors; Part I Case Study; Chapter 1 Bacillus and the Story of Protein Secretion and Production; 1.1 Bacillus as a Production Host: Introduction and Historical Account; 1.2 The Building of a Production Strain: Genetic Tools for B. subtilis Manipulation; 1.2.1 Promoters; 1.2.2 Vectors for Building a Production Strain; 1.2.3 B. subtilis Competent Cell Transformation; 1.2.4 Protoplasts-Mediated Manipulations; 1.2.5 Genetics by Electroporation; 1.3 B. subtilis Secretion System and Heterologous Protein Production 
505 8 |a 1.3.1 Bacillus Fermentation and Recovery of Industrial Enzyme1.3.2 Fermentation Stoichiometry; 1.3.3 Fermentor Kinetics and Outputs; 1.3.4 Downstream Processing; 1.4 Summary; References; Chapter 2 New Expression Systems for GPCRs; 2.1 Introduction; 2.2 Recombinant GPCR Production -- Traditional Approaches for Achieving High-Level Production; 2.3 Engineered Expression Systems for GPCR Production; 2.3.1 Bacteria; 2.3.2 Yeasts; 2.3.3 Insect Cells; 2.3.4 Mammalian Cells; 2.3.5 Transgenic Animals; 2.3.6 Cell-Free Systems; 2.4 Conclusion; References; Chapter 3 Glycosylation; 3.1 Introduction 
505 8 |a 3.2 Types of Glycosylation3.2.1 N-linked Glycans; 3.2.2 O-linked Glycans; 3.3 Factors Affecting Glycosylation; 3.3.1 Nutrient Depletion; 3.3.2 Fed-batch Cultures and Supplements; 3.3.3 Specific Culture Supplements; 3.3.4 Ammonia; 3.3.5 pH; 3.3.6 Oxygen; 3.3.7 Host Cell Systems; 3.3.8 Other Factors; 3.4 Modification of Glycosylation; 3.4.1 siRNA and Gene Knockout/Knockin; 3.4.2 Glycoprotein Processing Inhibitors and In Vitro Modification of Glycans; 3.5 Glycosylation Analysis; 3.5.1 Release of Glycans from Glycoproteins; 3.5.2 Derivatization of Glycans; 3.6 Methods of Analysis 
505 8 |a 3.6.1 Lectin Arrays3.6.2 Liquid Chromatography; 3.6.2.1 HILIC Analysis; 3.6.2.2 Reversed Phase (RP) and Porous Graphitic Carbon (PGC) Chromatography; 3.6.2.3 Weak Anion Exchange (WAX) HPLC Analysis; 3.6.2.4 High pH Anion Exchange Chromatography with Pulsed Amperometric Detection (HPAEC-PAD); 3.6.3 Capillary Electrophoresis (CE); 3.6.4 Fluorophore-assisted Carbohydrate Electrophoresis (FACE) and CGE-LIF; 3.6.5 Mass Spectrometry (MS); 3.6.5.1 Ionization; 3.6.5.2 Derivatization Techniques Used for MS Analysis of Glycans; 3.6.5.3 Fragmentation of Carbohydrates; 3.7 Conclusion; References 
505 8 |a Part II BioreactorsChapter 4 Bioreactors for Stem Cell and Mammalian Cell Cultivation; 4.1 Overview of (Mammalian and Stem) Cell Culture Engineering; 4.1.1 Cell Products for Therapeutics; 4.1.2 Cell as a Product: Stem Cells; 4.2 Bioprocess Characterization; 4.2.1 Cell Cultivation Methods; 4.2.2 Cell Metabolism; 4.2.3 Culture Medium Design; 4.2.4 Culture Parameters; 4.2.5 Culture Modes; 4.3 Cell Culture Systems; 4.3.1 Static Culture Systems; 4.3.2 Roller Bottles; 4.3.3 Spinner Flask; 4.3.4 Airlift Bioreactor; 4.3.5 Fixed/Fluidized-Bed Bioreactor; 4.3.6 Wave Bioreactor 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Pharmaceutical biotechnology industry. 
650 0 |a Biotechnological process monitoring. 
650 0 |a Pharmaceutical technology. 
650 0 |a Bioreactors. 
650 1 2 |a Biological Products  |x chemistry 
650 2 2 |a Drug Compounding 
650 2 2 |a Technology, Pharmaceutical 
650 2 2 |a Bioreactors 
650 6 |a Biotechnologie pharmaceutique  |x Industrie. 
650 6 |a Procédés biotechnologiques  |x Surveillance. 
650 6 |a Techniques pharmaceutiques. 
650 6 |a Bioréacteurs. 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a Pharmaceutical technology  |2 fast 
650 7 |a Bioreactors  |2 fast 
650 7 |a Biotechnological process monitoring  |2 fast 
650 7 |a Pharmaceutical biotechnology industry  |2 fast 
700 1 |a Komives, Claire,  |e editor. 
700 1 |a Zhou, Weichang,  |d 1963-  |e editor. 
758 |i has work:  |a Bioprocessing technology for production of biopharmaceuticals and bioproducts (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGdPQhKHB3th6qTXhy43pK  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Bioprocessing technology for production of biopharmaceuticals and bioproducts.  |b First edition.  |d Hoboken, NJ : John Wiley & Sons, Inc., 2018  |z 9781118361986  |w (DLC) 2018036496 
830 0 |a Wiley series in biotechnology and bioengineering. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=5612900  |z Texto completo 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL5612900 
938 |a EBSCOhost  |b EBSC  |n 1985274 
994 |a 92  |b IZTAP