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Algorithms for next-generation sequencing /

Bibliographic Details
Call Number:Libro Electrónico
Main Author: Sung, Wing-Kin (Author)
Format: Electronic eBook
Language:Inglés
Published: Boca Raton : CRC Press, [2017]
Series:Chapman and Hall/CRC mathematical & computational biology series.
Subjects:
Online Access:Texto completo
Table of Contents:
  • Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; 1: Introduction; 1.1 DNA, RNA, protein and cells ; 1.2 Sequencing technologies ; 1.3 First-generation sequencing.
  • 1.4 Second-generation sequencing 1.4.1 Template preparation ; 1.4.2 Base calling.
  • 1.4.3 Polymerase-mediated methods based on reversible terminator nucleotides 1.4.4 Polymerase-mediated methods based on unmodied nucleotides; 1.4.5 Ligase-mediated method.
  • 1.5 Third-generation sequencing 1.5.1 Single-molecule real-time sequencing ; 1.5.2 Nanopore sequencing method.
  • 1.5.3 Direct imaging of DNA using electron microscopy 1.6 Comparison of the three generations of sequencing ; 1.7 Applications of sequencing.