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|a UAMI
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100 |
1 |
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|a Crichton, Robert R.,
|e author.
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245 |
1 |
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|a Metal-based neurodegeneration :
|b from molecular mechanisms to therapeutic strategies /
|c Robert Crichton and Roberta Ward.
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250 |
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|a Second edition.
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264 |
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1 |
|a Chichester, West Sussex :
|b John Wiley & Sons, Ltd.,
|c 2014.
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300 |
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|a 1 online resource (439 pages) :
|b illustrations (chiefly color)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
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|a Includes bibliographical references and index.
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|a Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases.
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|a Online resource; title from electronic title page (ebrary, viewed on March 4, 2015).
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|a Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scient.
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590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Nervous system
|x Degeneration
|x Etiology.
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650 |
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|a Brain
|x Pathophysiology.
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650 |
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|a Oxidative stress.
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650 |
|
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|a Metals
|x Health aspects.
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650 |
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2 |
|a Neurodegenerative Diseases
|x etiology
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650 |
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2 |
|a Neurodegenerative Diseases
|x metabolism
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650 |
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2 |
|a Brain
|x physiology
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650 |
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2 |
|a Metals
|x adverse effects
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2 |
|a Oxidative Stress
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650 |
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|a Cerveau
|x Physiopathologie.
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650 |
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6 |
|a Stress oxydatif.
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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|a MEDICAL
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650 |
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|a MEDICAL
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|2 bisacsh
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650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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650 |
|
7 |
|a Brain
|x Pathophysiology
|2 fast
|
650 |
|
7 |
|a Metals
|x Health aspects
|2 fast
|
650 |
|
7 |
|a Oxidative stress
|2 fast
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655 |
|
4 |
|a Internet Resources.
|
700 |
1 |
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|a Ward, Roberta J.,
|e author.
|
758 |
|
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|i has work:
|a Metal-based neurodegeneration (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGvqPHX3Dqt6PQ3DqKPtgC
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
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|i Print version:
|a Crichton, Robert R.
|t Metal-based neurodegeneration.
|b 2nd ed.
|d Chichester, West Sussex, U.K. : John Wiley & Sons, 2013
|z 9781119977148
|w (DLC) 2012048288
|w (OCoLC)820532743
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=1380164
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