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Metal-based neurodegeneration : from molecular mechanisms to therapeutic strategies /

Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeosta...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Crichton, Robert R. (Autor), Ward, Roberta J. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester, West Sussex : John Wiley & Sons, Ltd., 2014.
Edición:Second edition.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Crichton, Robert R.,  |e author. 
245 1 0 |a Metal-based neurodegeneration :  |b from molecular mechanisms to therapeutic strategies /  |c Robert Crichton and Roberta Ward. 
250 |a Second edition. 
264 1 |a Chichester, West Sussex :  |b John Wiley & Sons, Ltd.,  |c 2014. 
300 |a 1 online resource (439 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases. 
588 0 |a Online resource; title from electronic title page (ebrary, viewed on March 4, 2015). 
520 |a Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scient. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Nervous system  |x Degeneration  |x Etiology. 
650 0 |a Brain  |x Pathophysiology. 
650 0 |a Oxidative stress. 
650 0 |a Metals  |x Health aspects. 
650 2 |a Neurodegenerative Diseases  |x etiology 
650 2 |a Neurodegenerative Diseases  |x metabolism 
650 2 |a Brain  |x physiology 
650 2 |a Metals  |x adverse effects 
650 2 |a Oxidative Stress 
650 6 |a Cerveau  |x Physiopathologie. 
650 6 |a Stress oxydatif. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Brain  |x Pathophysiology  |2 fast 
650 7 |a Metals  |x Health aspects  |2 fast 
650 7 |a Oxidative stress  |2 fast 
655 4 |a Internet Resources. 
700 1 |a Ward, Roberta J.,  |e author. 
758 |i has work:  |a Metal-based neurodegeneration (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGvqPHX3Dqt6PQ3DqKPtgC  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |a Crichton, Robert R.  |t Metal-based neurodegeneration.  |b 2nd ed.  |d Chichester, West Sussex, U.K. : John Wiley & Sons, 2013  |z 9781119977148  |w (DLC) 2012048288  |w (OCoLC)820532743 
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