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Biosynthesis of heterocycles : from the isolation to gene cluster /

This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Diana, Patrizia
Otros Autores: Cirrincione, Girolamo
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, New Jersey : Wiley, [2015]
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Diana, Patrizia. 
245 1 0 |a Biosynthesis of heterocycles :  |b from the isolation to gene cluster /  |c Patrizia Diana, Girolamo Cirrincione. 
264 1 |a Hoboken, New Jersey :  |b Wiley,  |c [2015] 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record and CIP data provided by publisher. 
505 0 |a Cover; Contents; Preface; Acknowledgments; Chapter 1 Introduction; 1.1 Natural Products: Primary and Secondary Metabolites; 1.2 Common Reactions in Secondary Metabolites; 1.2.1 Alkylations; 1.2.2 Wagner-Meerwein Rearrangements; 1.2.3 Aldol and Claisen Reactions; 1.2.4 Schiff Base Formation and Mannich Reactions; 1.2.5 Transaminations; 1.2.6 Decarboxylations; 1.2.7 Oxidation and Reduction Reactions; 1.2.8 Dehalogenation/Halogenation Reactions; 1.2.9 Glycosylation Reactions; References; Chapter 2 Techniques for Biosynthesis; 2.1 Isotopic Labeling; 2.1.1 Stable Isotopes 
505 8 |a 2.1.2 Radioactive Isotopes2.2 Gene Coding for Enzymes; 2.3 Combinatorial Biosynthesis; References; Chapter 3 Three-Membered Heterocyclic Rings and Their Fused Derivatives; 3.1 Aziridines and Azirines; 3.1.1 Azicemicins; 3.1.2 Miraziridine; 3.1.3 Maduropeptin; 3.1.4 Azinomycins; 3.1.5 Ficellomycin; 3.1.6 Mitomycins; 3.1.7 Azirinomycin and Related Azirines; 3.2 Oxiranes and Oxirenes; 3.2.1 Fosfomycin; 3.2.2 AK, HC, and AF toxins; 3.2.3 Cerulenin; 3.2.4 Polyhydroxyalkanoates; 3.2.5 Epoxyrollins; 3.2.6 Asperlactone, Aspyrone, Asperline; 3.2.7 Tajixanthone; 3.2.8 Cyclomarin; 3.2.9 Cyclopenin 
505 8 |a 3.2.10 Ovalicin and Fumagillin3.2.11 Methylenomycin A; 3.2.12 Antibiotic LL-C10037; 3.2.13 Manumycins; 3.2.14 Scopolamine; 3.2.15 Iridoid Glucosides; 3.2.16 Cordiaquinone; 3.2.17 Cyclizidine and Indolizomycin; 3.2.18 Enediyne Antibiotics; 3.2.19 Macrolides; 3.2.20 Epothilones; 3.2.21 Pimaricin; 3.2.22 Hypothemycin; 3.2.23 Radicicol and Monocillin I; 3.2.24 Trichothecenes; 3.2.25 Sporolides A and B; References; Chapter 4 Four-Membered Heterocyclic Rings and Their Fused Derivatives; 4.1 Azetidine and Azetines; 4.1.1 Azetidine-2-carboxylic acid; 4.1.2 Polyoxins; 4.1.3 Mugineic Acids 
520 |a This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working withheterocycles. Covers methods and techniques: isotopic labelling, enzymes and mutants, and pathway identification Provides a thorough resource of informationspecifically on heterocyclic natural products and their practicalbiosynthetic relevance Explains the role of natural products in chemistry a. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Heterocyclic compounds  |x Synthesis. 
650 0 |a Biosynthesis. 
650 6 |a Composés hétérocycliques  |x Synthèse. 
650 6 |a Biosynthèse. 
650 7 |a SCIENCE  |x Chemistry  |x Organic.  |2 bisacsh 
650 7 |a Biosynthesis  |2 fast 
650 7 |a Heterocyclic compounds  |x Synthesis  |2 fast 
700 1 |a Cirrincione, Girolamo. 
758 |i has work:  |a Biosynthesis of Heterocycles [electronic resource] (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCY3TTY47jYDxvYpGJy6VG3  |4 https://id.oclc.org/worldcat/ontology/hasWork 
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