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Advances in Medicine and Biology.

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Berhardt, Leon V.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hauppauge : Nova Science Publishers, Incorporated, April 2011.
Colección:Advances in Medicine and Biology Ser.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ADVANCES IN MEDICINE AND BIOLOGY. VOLUME 20; ADVANCES IN MEDICINE AND BIOLOGY. VOLUME 20 ; CONTENTS ; PREFACE ; TROPONIN T: A SEARCH OF SUPERPARAMAGNETIC IRON-OXIDE BOUND ANTITROPONIN NANOPARTICLE FOR MAGNETIC RESONANCE IMAGING ; Abstract ; Introduction ; 2. Materials and Methods ; 2.1. Preparation and Characterization of Nonoparticle Complex ; 2.2. Gadolinium Enhanced T1 Weighted Imaging of Apoferritin-Gadolinium Complex ; 2.3. Characterization of Cardiac Troponin T/I/C Subtypes and MALDI Imaging.
  • 2.4. Development of Antitroponin Based Nanoparticles as MRI Imaging Contrast Agents Selection of TE and TR for Optimizing Contrast ; 2.5. MRI Microimaging of Heart and Prototype Tube ; 2.6. Characterization, Detection of and Measurement of Cardiac Muscle Components ; 3. Results ; 3.1. The Polymer Coated Superparamagnetic Biotinylated Antitroponint Microspheres as Image Contrast ; 3.2. Gadolinium Enhanced T1 Weighted Imaging of Apoferritin-Gadolinium Complex ; 3.3. Characterization of Cardiac Troponin T/I/C Subtypes and MALDI Imaging.
  • 3.4. High Resolution Magnetic Resonance Imaging of Nanoparticles and Post-Injected Mouse Heart 3.5. Characterization, Detection of and Measurement of Cardiac Muscle Components ; 4. Discussion ; 5. Limitations and Challenges of the Study ; 6. The Futuristic View of Art ; 7. Conclusion ; Acknowledgments ; References ; TROPONIN T: NEWER MAGNETIC IMMUNOASSAY METHOD OF TROPONINS AS POINT-OF-CARE DETECTION OF ACUTE MYOCARDIAL INFARCTION ; Abstract ; 1. Introduction ; 1.2. Synthesis of Nanomagnetic Particles for Biomedical Applications.
  • 1.3. Characterization of Antitroponin Based Nanoparticle Complex by Sandwich ELISA 1.4. Principle of Nanoparticle in Magnetic Assay ; 2. AMI Detectable Device ; 2.1. The POCM Device ; 2.2. Device for Acute Myocardial Infarction Detection and Troponin Screening ; 2.3. Principle of Dry Chemistry Glucodetection in Troponin Estimation ; 2.4. Calibration of Glucose Measurement ; 2.2. The Use of the Fluorescent Dry Chemistry in Glucodetection Device ; 3. Detection of Troponin T as Point-of-Care AMI Test ; 4. Approach of Troponin MALDI Analysis.
  • 5. MALDI-TOF Analysis in AMI Serum 6. Limitations ; Conclusion ; Acknowledgments ; References ; GENOTOXICITY EVALUATION OF EXPOSURE TO LEAD ; ABSTRACT ; 1. INTRODUCTION ; 1.1. Lead Modes of Action ; Interaction with Sulphydryl Groups of Proteins ; Supplanting of Essential Polyvalent Cations ; Free Radical Production ; 1.2. Genotoxicity Tests ; 2. HYPOXANTHINE-GUANINE PHOSPHORIBOSYL- TRANSFERASE GENE MUTATION ASSAY ; 3. T CELL RECEPTOR MUTATION ASSAY ; 4. CHROMOSOME ABERRATIONS ; 4.1. In Vitro Studies ; 4.2. In Vivo Studies ; 4.3. Epidemiological Studies.