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Phytonutrients /

Plants are a major source of nutrition in our diet, and offer an array of health benefits, yet many Western diets are still over-reliant upon animal-based foods. Growing evidence suggests that this emphasis on foods of animal origin may be linked to increased incidences of cancer and cardiovascular...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Salter, Andrew M., Wiseman, Helen, Tucker, G. A. (Gregory A.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester, West Sussex, UK ; Hoboken : Wiley-Blackwell, 2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Phytonutrients
  • Contents
  • Preface
  • Contributors
  • Abbreviations
  • 1 Plant foods and health
  • Introduction
  • Historical changes in the plant content of the human diet
  • Changing composition of dietary constituents in the past 50 years
  • Plants
  • nutrients and other constituents
  • A summary of the evidence linking plant food intake and health
  • Coronary heart disease and stroke
  • Fruits and vegetables
  • Pulses and nuts
  • Cereals
  • Antioxidant nutrients
  • Other bioactive substances
  • Antioxidant hypothesis
  • Phytosterols and -stanols
  • Conclusions for coronary heart disease and stroke
  • Cancer
  • Fruit and vegetables
  • Legumes and nuts
  • Foods containing fibre
  • Vitamins
  • Other plant-derived substances
  • Conclusions for cancer
  • Type 2 diabetes
  • Age-related macular degeneration and cataract
  • Age-related cognitive decline
  • Chronic obstructive pulmonary disease
  • Osteoporosis and bone health
  • Plant foods and health: overall conclusions
  • Recommendations and current policy on plant food intake
  • Fruit and vegetables
  • Wholegrain foods
  • Current consumption patterns
  • Conclusions
  • Acknowledgement
  • 2 Carbohydrates and lipids
  • Introduction
  • Major carbohydrates
  • Sugars
  • Polysaccharides
  • Starch
  • Cell wall polymers
  • Biosynthesis of cell wall polymers
  • Cell wall turnover
  • Nutritional benefits of plant carbohydrates
  • Major sources of dietary fibre within the diet and recommended intakes
  • Definition and measurement of dietary fibre
  • Physiological effects of dietary fibre
  • Lipids
  • Synthesis of fatty acids in plants
  • Synthesis of glycerolipids in plants
  • Modification of plant lipids
  • Fatty acid composition of plant foods
  • Vegetables
  • Cereals
  • Fruit
  • Oil seeds
  • Dietary lipids and human health
  • Phytosterols
  • 3 Carotenoids
  • Introduction.
  • Structure, biosynthesis and function of plant carotenoids
  • Dietary sources and health benefits
  • Absorption and bioavailability of dietary carotenoids
  • Carotenoid type
  • Food matrix
  • Carotenoid metabolism in humans
  • Meeting the dietary demand and consequences for imbalance
  • Acknowledgements
  • 4 Polyphenols
  • Introduction
  • Polyphenol structure
  • Phenolic acids and stilbenes
  • Flavonoids
  • Biosynthetic routes within the plant
  • Shikimic precursor and benzoic acid biosynthesis
  • Cinnamic acid biosynthesis
  • Stilbene biosynthesis
  • Flavonoid biosynthesis
  • Major sources within the diet
  • Phenolic acids and stilbenes
  • Flavonoids
  • Flavonols
  • Flavanones
  • Flavanols
  • Flavones
  • Anthocyanins
  • Isoflavones
  • Metabolic fate of dietary polyphenols
  • Gastrointestinal tract metabolism
  • Colonic metabolism
  • Role in human health
  • Flavonoids as classical antioxidants
  • Non-antioxidant activities of flavonoids
  • Interactions with cell signalling pathways
  • Other potential mechanisms of action
  • Conclusion
  • Summary
  • Acknowledgements
  • 5 Vitamins C and E
  • Introduction
  • Vitamin C: structure and chemistry
  • Dietary sources of vitamin C
  • Vitamin C: biosynthesis and metabolism in plants
  • Vitamin C functions in plants
  • Vitamin C manipulation in plants
  • Absorption and transport of vitamin C in mammals
  • Vitamin E: structure and chemistry
  • Dietary sources of vitamin E
  • Vitamin E: biosynthetic pathways
  • Roles of tocochromanols in plants
  • Manipulation of tocochromanol concentration
  • Absorption and transport of vitamin E in mammals
  • Antioxidant functions of vitamin E
  • 6 Folate
  • Introduction
  • One-carbon metabolism
  • Generation and interconversion of C1-units
  • Serine-glycine metabolism
  • Formate activation
  • Histidine catabolism
  • Interconvertion of C1-substituted folates.
  • Utilisation of C1-units
  • Methionine synthesis
  • Purine ring formation
  • Formylation of methionyl-tRNA
  • Thymidylate synthesis
  • Pantothenate synthesis
  • Folate synthesis and distribution in plants
  • Biosynthesis of tetrahydrofolate in plants
  • Pterin branch
  • pABA branch
  • Assembly of the pterin, pABA and glutamate moieties
  • Reduction and polyglutamylation
  • Catabolism and salvage pathway
  • Compartmentation and transport of folates
  • Subcellular location of folates
  • Folate transporters
  • Folates distribution in plants
  • Physiology of folate in human health and disease
  • Absorption
  • Transport, storage, catabolism and excretion
  • Metabolic and clinical manifestations of folate deficiency
  • Diagnosis of folate deficiency
  • Folate bioavailability, requirements and food fortification
  • Bioavailability
  • Dietary intake recommendations
  • Dietary sources of folate
  • Food fortification
  • Prospects for plant foods biofortification
  • 7 Phytoestrogens
  • Introduction
  • Biosynthesis of phytoestrogens
  • Introduction
  • Isoflavonoids
  • Prenylated flavonoids
  • Stilbenes
  • Lignans
  • Genetic engineering
  • Isoflavonoids
  • Introduction
  • Dietary sources and intakes
  • Metabolism and bioavailability
  • Isoflavonoids and cancer prevention
  • Hormone-dependent cancer prevention by isoflavonoids
  • Oestrogens and risk of breast cancer
  • Oestrogen receptor-mediated events
  • Animal models
  • Mechanisms of anticancer action of isoflavonoids
  • Clinical studies
  • Protection by isoflavonoids against cardiovascular disease
  • Cholesterol-lowering and isoflavonoids
  • Antioxidant action
  • Arterial function
  • Cellular effects
  • Protection by isoflavonoids against osteoporosis, cognitive decline and menopausal symptoms?
  • Osteoporosis
  • Menopausal symptoms and cognitive decline
  • Isoflavonoids: potential risks
  • Lignans.
  • Introduction
  • Production of mammalian lignans
  • Cardiovascular disease
  • Breast cancer prevention
  • Prostate cancer prevention
  • Prevention of other types of cancer
  • Other health benefits
  • Prenylflavonoids
  • Stilbenes
  • Miroestrol
  • Deoxybenzoins
  • Coumestans
  • Phytoestrogens and human health: conclusions
  • 8 Plant minerals
  • Introduction
  • Genetic variation in plant mineral concentration
  • Introduction
  • Between-species genetic variation in plant mineral concentration
  • Within-species genetic variation in plant mineral concentration
  • Iron and zinc
  • Iodine and selenium
  • Calcium and magnesium
  • Copper
  • Has the mineral concentration of crops declined due to breeding for increased yield?
  • Evidence for a decline in mineral concentration of horticultural crops
  • Is there evidence for a decline in mineral concentration of staple crops?
  • A case study on potatoes
  • a précis of White et al. (2009)
  • Index.