Clinical trial design : Bayesian and frequentist adaptive methods /

There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This bo...

Full description

Bibliographic Details
Call Number:Libro Electrónico
Main Author: Yin, Guosheng (Author)
Format: Electronic eBook
Language:Inglés
Published: Hoboken, N.J. : John Wiley & Sons, ©2012.
Series:Wiley series in probability and statistics.
Subjects:
Clinical trials > Statistical methods.
Bayesian statistical decision theory.
Mathematical statistics.
Clinical Trials as Topic > methods
Bayes Theorem
Statistics as Topic > methods
Études cliniques > Méthodes statistiques.
Théorie de la décision bayésienne.
Théorème de Bayes.
MEDICAL > Laboratory Medicine.
Bayesian statistical decision theory
Clinical trials > Statistical methods
Mathematical statistics
Online Access:Texto completo
Table of Contents:
  • Front Matter
  • Introduction
  • Fundamentals of Clinical Trials
  • Frequentist versus Bayesian Statistics
  • Phase I Trial Design
  • Phase II Trial Design
  • Phase III Trial Design
  • Adaptive Randomization
  • Late-Onset Toxicity
  • Drug-Combination Trials
  • Targeted Therapy Design
  • References
  • Author Index
  • Subject Index
  • Wiley Series in Probability and Statistics.
  • Fundamentals of clinical trials
  • Frequentist versus Bayesian statistics
  • Phase I trial design
  • Phase II trial design
  • Phase III trial design
  • Adaptive randomization
  • Late onset toxicity
  • Drug combination trials
  • Targeted therapy design.

Similar Items