Cargando…
Cancer on trial : oncology as a new style of practice /
This title charts the emergence of a clinical field - medical oncology - for which experimental protocols have become routinized as a form of normal practice.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Chicago :
University of Chicago Press,
©2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | EBOOKCENTRAL_ocn774293514 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
| 006 | m o d | ||
| 007 | cr cn||||||||| | ||
| 008 | 110505s2012 ilua ob 001 0 eng d | ||
| 040 | |a E7B |b eng |e pn |c E7B |d CDX |d N$T |d VPI |d YDXCP |d OCLCQ |d OCLCF |d OTZ |d EBLCP |d IDEBK |d DEBSZ |d OCLCQ |d STBDS |d COCUF |d CNNOR |d LOA |d MERUC |d STF |d AGLDB |d USU |d MOR |d ICA |d FVL |d ZCU |d OCLCQ |d U3G |d OCLCO |d OCLCA |d U3W |d OCLCA |d D6H |d WRM |d VTS |d ICG |d VT2 |d AU@ |d OCLCO |d WYU |d G3B |d OCLCO |d OCLCA |d TKN |d OCLCO |d LEAUB |d AUW |d BTN |d INTCL |d MHW |d SNK |d OCLCO |d DKC |d OCLCQ |d OCLCO |d OCLCQ |d OCLCA |d AJS |d OCLCO |d OCL |d OCLCQ |d SFB |d OCLCQ |d OCLCO |d OCLCL |d OCLCQ |d OCLCL |d OCLCQ | ||
| 019 | |a 772845694 |a 778618126 |a 816876782 |a 1055368631 |a 1066605961 |a 1081266156 | ||
| 020 | |a 9780226428932 |q (electronic bk.) | ||
| 020 | |a 0226428931 |q (electronic bk.) | ||
| 020 | |a 9786613362612 | ||
| 020 | |a 6613362611 | ||
| 020 | |a 1283362619 | ||
| 020 | |a 9781283362610 | ||
| 020 | |z 0226428915 |q (cloth alk. paper) | ||
| 020 | |z 9780226428918 |q (cloth ; |q alk. paper) | ||
| 029 | 1 | |a AU@ |b 000051829540 | |
| 029 | 1 | |a DEBBG |b BV040093363 | |
| 029 | 1 | |a DEBBG |b BV042793538 | |
| 029 | 1 | |a DEBSZ |b 379326140 | |
| 029 | 1 | |a DEBSZ |b 48984507X | |
| 029 | 1 | |a NZ1 |b 14693879 | |
| 035 | |a (OCoLC)774293514 |z (OCoLC)772845694 |z (OCoLC)778618126 |z (OCoLC)816876782 |z (OCoLC)1055368631 |z (OCoLC)1066605961 |z (OCoLC)1081266156 | ||
| 043 | |a e------ |a n-us--- | ||
| 050 | 4 | |a RC254.5 |b .K43 2012eb | |
| 060 | 4 | |a QZ 11 AA1 | |
| 072 | 7 | |a HEA |x 039030 |2 bisacsh | |
| 072 | 7 | |a MED |x 062000 |2 bisacsh | |
| 072 | 7 | |a MJCL |2 bicssc | |
| 082 | 0 | 4 | |a 616.99/40072 |2 23 |
| 084 | |a XH 3200 |2 rvk | ||
| 049 | |a UAMI | ||
| 100 | 1 | |a Keating, Peter, |d 1953- |1 https://id.oclc.org/worldcat/entity/E39PBJhMjDChX7b7Dg3K89Xjmd | |
| 245 | 1 | 0 | |a Cancer on trial : |b oncology as a new style of practice / |c Peter Keating and Alberto Cambrosio. |
| 260 | |a Chicago : |b University of Chicago Press, |c ©2012. | ||
| 300 | |a 1 online resource (xviii, 456 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a From "nonentity" to global network: the rise of a new style of biomedical practice -- An early career in clinical oncology -- About this book -- A capsule history of cancer clinical trials -- Cancer clinical trials as a new style of practice -- The protocol -- Before there were trials -- Cancer hospitals and cancer institutes -- Diagnosing cancer -- Treating cancer -- Prognosticating cancer -- Testing therapies -- The emergence of clinical cancer research (1955-66) -- A landmark clinical trial -- Curing leukemia: the vamp trial -- A collective undertaking -- The elements of innovation -- What about the patients? -- The collective turn: cooperative groups as epistemic organizations -- Assembling the US cooperative system -- Screening for drugs: from mice to humans -- Tinkering with the cooperative group structure -- Meanwhile in Europe -- Clinical trial statistics -- What is a random sample? -- What is statistical significance? -- Statisticians, statistics, and early cooperative clinical trials -- Statisticians at the NIH -- Statisticians in Paris -- Fabricating the tools of the trade -- Controversial methods -- The emergence of the phase system -- Criticism and the redefinition of clinical cancer trials as an autonomous form of research -- Clinical cancer research under fire -- The reorganization of screening and clinical trials in the United States -- Surgery and radiotherapy in the cooperative groups -- An avalanche of numbers from the new style of practice (1965-89) -- A web of trials -- Breast cancer and its trials -- The lessons of the breast cancer trials -- The emergence of combination chemotherapy -- The multiple meanings of breast cancer trials -- Statisticians, data centers, and the organization of large-scale clinical trials -- Centers of calculation: us statisticians and the data center -- The mechanics of data production -- Meanwhile in Europe, take two -- Back in the USA: group statisticians and NCI statisticians -- Insiders' dissent: the randomization debate -- A relational space of substances and regimens -- The clinical evaluation of substances -- Screening substances: the animal screen -- Procuring compounds -- Oncopolitics? reshaping collaborative research -- Centralization or coordination? the European debate -- Clinical trials as clinical research: the US debate -- Oncology in the community -- Targeted therapy, targeted trials (1990-2006) -- Second interlude: molecular biology and oncogenes -- The rise of molecular biology -- Cancer and molecular biology: 1960-80 -- The clinical isolation of human oncogenes -- Oncogenes and oncoproteins since 1982 -- Magic bullets? the Gleevec trials -- Molecular biology and targeted substances -- The trials of a targeted therapy -- Where did Gleevec come from? -- Monitoring data, managing risks -- A medical oncologist and his patients -- Patients and activists -- Targeted therapy and clinical cancer research -- Introduction: molecular biology and translational research -- Molecular biology and the US cooperative groups -- The reorganization of the drug discovery process and the transformation of the NCI screen -- Clinical trials in a targeted age -- More oncopolitics -- Looking back and looking forward -- The observational alternative to clinical cancer trials -- Comparative effectiveness and clinical trials. | |
| 588 | 0 | |a Print version record. | |
| 520 | 8 | |a This title charts the emergence of a clinical field - medical oncology - for which experimental protocols have become routinized as a form of normal practice. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Oncology |x Research. | |
| 650 | 0 | |a Cancer |x Research. | |
| 651 | 0 | |a Europe. | |
| 650 | 1 | 2 | |a Clinical Trials as Topic |x history |
| 650 | 1 | 2 | |a Medical Oncology |x history |
| 650 | 2 | 2 | |a Molecular Targeted Therapy |x history |
| 650 | 2 | 2 | |a Neoplasms |x therapy |
| 651 | 2 | |a Europe | |
| 651 | 2 | |a United States | |
| 650 | 6 | |a Cancérologie |x Recherche. | |
| 650 | 6 | |a Cancer |x Recherche. | |
| 651 | 6 | |a Europe. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
| 650 | 7 | |a Cancer |x Research |2 fast | |
| 650 | 7 | |a Oncology |x Research |2 fast | |
| 651 | 7 | |a Europe |2 fast |1 https://id.oclc.org/worldcat/entity/E39PBJxCxPbbk4CPJDQJb4r6rq | |
| 700 | 1 | |a Cambrosio, Alberto, |d 1950- |1 https://id.oclc.org/worldcat/entity/E39PBJmp9Q3tWb3twc87XWgFrq | |
| 758 | |i has work: |a Cancer on trial (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGV3bXDvG7f7396jJYGcxC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Keating, Peter, 1953- |t Cancer on trial. |d Chicago : The University of Chicago Press, ©2012 |z 9780226428918 |w (DLC) 2011019445 |w (OCoLC)713181629 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=836879 |z Texto completo |
| 938 | |a Coutts Information Services |b COUT |n 20346124 | ||
| 938 | |a ebrary |b EBRY |n ebr10519567 | ||
| 938 | |a EBSCOhost |b EBSC |n 412486 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n 336261 | ||
| 938 | |a Oxford University Press USA |b OUPR |n EDZ0000157685 | ||
| 938 | |a YBP Library Services |b YANK |n 7298144 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL836879 | ||
| 994 | |a 92 |b IZTAP | ||