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Evidence synthesis for decision making in healthcare /

In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aim...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Welton, Nicky J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester, West Sussex : Wiley, 2012.
Colección:Statistics in practice.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Evidence synthesis for decision making in healthcare /  |c Nicky J. Welton [and others]. 
260 |a Chichester, West Sussex :  |b Wiley,  |c 2012. 
300 |a 1 online resource 
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490 1 |a Statistics in practice 
504 |a Includes bibliographical references and index. 
505 0 |6 880-01  |a Introduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design. 
588 0 |a Print version record and CIP data provided by publisher. 
520 |a In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixe. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Health services administration. 
650 0 |a Evidence-based medicine. 
650 0 |a Bayesian statistical decision theory. 
650 0 |a Decision making  |x Mathematical models. 
650 0 |a Statistics. 
650 2 |a Decision Support Techniques 
650 2 |a Statistics as Topic 
650 2 |a Evidence-Based Medicine  |x economics 
650 2 |a Models, Statistical 
650 2 |a Patient Care Management  |x methods 
650 2 |a Patient Care Management 
650 2 |a Health Services Administration 
650 2 |a Evidence-Based Medicine 
650 2 |a Evidence-Based Practice 
650 6 |a Services de santé  |x Administration. 
650 6 |a Médecine factuelle. 
650 6 |a Théorie de la décision bayésienne. 
650 6 |a Prise de décision  |x Modèles mathématiques. 
650 6 |a Statistiques. 
650 6 |a Statistique. 
650 7 |a statistics.  |2 aat 
650 7 |a MEDICAL  |x Administration.  |2 bisacsh 
650 7 |a MEDICAL  |x Practice Management & Reimbursement.  |2 bisacsh 
650 7 |a Statistics  |2 fast 
650 7 |a Decision making  |x Mathematical models  |2 fast 
650 7 |a Bayesian statistical decision theory  |2 fast 
650 7 |a Evidence-based medicine  |2 fast 
650 7 |a Health services administration  |2 fast 
655 4 |a Internet Resources. 
700 1 |a Welton, Nicky J. 
758 |i has work:  |a Evidence synthesis for decision making in healthcare (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCG3hPVYrycKpkv4ctyhtBq  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Evidence synthesis for decision making in healthcare.  |d Chichester, West Sussex : John Wiley & Sons, 2012  |z 9780470061091  |w (DLC) 2011051684 
830 0 |a Statistics in practice. 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=881533  |z Texto completo 
880 0 0 |6 505-01/(S  |g Machine generated contents note:  |g 1.1.  |t rise of health economics --  |g 1.2.  |t Decision making under uncertainty --  |g 1.2.1.  |t Deterministic models --  |g 1.2.2.  |t Probabilistic decision modelling --  |g 1.3.  |t Evidence-based medicine --  |g 1.4.  |t Bayesian statistics --  |g 1.5.  |t NICE --  |g 1.6.  |t Structure of the book --  |g 1.7.  |t Summary key points --  |g 1.8.  |t Further reading --  |t References --  |g 2.1.  |t Introduction to Bayesian methods --  |g 2.1.1.  |t What is a Bayesian approach--  |g 2.1.2.  |t Likelihood --  |g 2.1.3.  |t Bayes' theorem and Bayesian updating --  |g 2.1.4.  |t Prior distributions --  |g 2.1.5.  |t Summarising the posterior distribution --  |g 2.1.6.  |t Prediction --  |g 2.1.7.  |t More realistic and complex models --  |g 2.1.8.  |t MCMC and Gibbs sampling --  |g 2.2.  |t Introduction to WinBUGS --  |g 2.2.1.  |t BUGS language --  |g 2.2.2.  |t Graphical representation --  |g 2.2.3.  |t Running WinBUGS --  |g 2.2.4.  |t Assessing convergence in WinBUGS --  |g 2.2.5.  |t Statistical inference in WinBUGS --  |g 2.2.6.  |t Practical aspects of using WinBUGS --  |g 2.3.  |t Advantages and disadvantages of a Bayesian approach --  |g 2.4.  |t Summary key points --  |g 2.5.  |t Further reading --  |g 2.6.  |t Exercises --  |t References --  |g 3.1.  |t Introduction --  |g 3.2.  |t Decision tree models --  |g 3.3.  |t Model parameters --  |g 3.3.1.  |t Effects of interventions --  |g 3.3.2.  |t Quantities relating to the clinical epidemiology of the clinical condition being treated --  |g 3.3.3.  |t Utilities --  |g 3.3.4.  |t Resource use and costs --  |g 3.4.  |t Deterministic decision tree --  |g 3.5.  |t Stochastic decision tree --  |g 3.5.1.  |t Presenting the results of stochastic economic decision models --  |g 3.6.  |t Sources of evidence --  |g 3.7.  |t Principles of synthesis for decision models (motivation for the rest of the book) --  |g 3.8.  |t Summary key points --  |g 3.9.  |t Further reading --  |g 3.10.  |t Exercises --  |t References --  |g 4.1.  |t Introduction --  |g 4.2.  |t Fixed Effect model --  |g 4.3.  |t Random Effects model --  |g 4.3.1.  |t predictive distribution --  |g 4.3.2.  |t Prior specification for τ --  |g 4.3.3.  |t 'Exact' Random Effects model for Odds Ratios based on a Binomial likelihood --  |g 4.3.4.  |t Shrunken study level estimates --  |g 4.4.  |t Publication bias --  |g 4.5.  |t Study validity --  |g 4.6.  |t Summary key points --  |g 4.7.  |t Further reading --  |g 4.8.  |t Exercises --  |t References --  |g 5.1.  |t Introduction --  |g 5.2.  |t Random effects meta-regression models --  |g 5.2.1.  |t Generic random effect meta-regression model --  |g 5.2.2.  |t Random effects meta-regression model for Odds Ratio (OR) outcomes using a Binomial likelihood --  |g 5.2.3.  |t Autocorrelation and centring covariates --  |g 5.3.  |t Limitations of meta-regression --  |g 5.4.  |t Baseline risk --  |g 5.4.1.  |t Model for including baseline risk in a meta-regression on the (log) OR scale --  |g 5.4.2.  |t Final comments on including baseline risk as a covariate --  |g 5.5.  |t Summary key points --  |g 5.6.  |t Further reading --  |g 5.7.  |t Exercises --  |t References --  |g 6.1.  |t Introduction --  |g 6.2.  |t Random Effects model revisited --  |g 6.3.  |t Assessing model fit --  |g 6.3.1.  |t Deviance --  |g 6.3.2.  |t Residual deviance --  |g 6.4.  |t Model comparison --  |g 6.4.1.  |t Effective number of parameters, pD --  |g 6.4.2.  |t Deviance Information Criteria --  |g 6.5.  |t Exploring inconsistency --  |g 6.5.1.  |t Cross-validation --  |g 6.5.2.  |t Mixed predictive checks --  |g 6.6.  |t Summary key points --  |g 6.7.  |t Further reading --  |g 6.8.  |t Exercises --  |t References --  |g 7.1.  |t Introduction --  |g 7.2.  |t Evaluation of decision models: One-stage vs two-stage approach --  |g 7.3.  |t Sensitivity analyses (of model inputs and model specifications) --  |g 7.4.  |t Summary key points --  |g 7.5.  |t Further reading --  |g 7.6.  |t Exercises --  |t References --  |g 8.1.  |t Introduction --  |g 8.2.  |t Prior and posterior simulation in a probabilistic model: Maple Syrup Urine Disease (MSUD) --  |g 8.3.  |t model for prenatal HIV testing --  |g 8.4.  |t Model criticism in multi-parameter models --  |g 8.5.  |t Evidence-based policy --  |g 8.6.  |t Summary key points --  |g 8.7.  |t Further reading --  |g 8.8.  |t Exercises --  |t References --  |g 9.1.  |t Why go beyond 'direct' head-to-head trials--  |g 9.2.  |t fixed treatment effects model for MTC --  |g 9.2.1.  |t Absolute treatment effects --  |g 9.2.2.  |t Relative treatment efficacy and ranking --  |g 9.3.  |t Random Effects MTC models --  |g 9.4.  |t Model choice and consistency of MTC evidence --  |g 9.4.1.  |t Techniques for presenting and understanding the results of MTC --  |g 9.5.  |t Multi-arm trials --  |g 9.6.  |t Assumptions made in mixed treatment comparisons --  |g 9.7.  |t Embedding an MTC within a cost-effectiveness analysis --  |g 9.8.  |t Extension to continuous, rate and other outcomes --  |g 9.9.  |t Summary key points --  |g 9.10.  |t Further reading --  |g 9.11.  |t Exercises --  |t References --  |g 10.1.  |t Introduction --  |g 10.2.  |t Continuous and discrete time Markov models --  |g 10.3.  |t Decision analysis with Markov models --  |g 10.3.1.  |t Evaluating Markov models --  |g 10.4.  |t Estimating transition parameters from a single study --  |g 10.4.1.  |t Likelihood --  |g 10.4.2.  |t Priors and posteriors for multinomial probabilities --  |g 10.5.  |t Propagating uncertainty in Markov parameters into a decision model --  |g 10.6.  |t Estimating transition parameters from a synthesis of several studies --  |g 10.6.1.  |t Challenges for meta-analysis of evidence on Markov transition parameters --  |g 10.6.2.  |t relationship between probabilities and rates --  |g 10.6.3.  |t Modelling study effects --  |g 10.6.4.  |t Synthesis of studies reporting aggregate data --  |g 10.6.5.  |t Incorporating studies that provide event history data --  |g 10.6.6.  |t Reporting results from a Random Effects model --  |g 10.6.7.  |t Incorporating treatment effects --  |g 10.7.  |t Summary key points --  |g 10.8.  |t Further reading --  |g 10.9.  |t Exercises --  |t References --  |g 11.1.  |t Introduction --  |g 11.2.  |t Deriving a prior distribution from observational evidence --  |g 11.3.  |t Bias allowance model for the observational data --  |g 11.4.  |t Hierarchical models for evidence from different study designs --  |g 11.5.  |t Discussion --  |g 11.6.  |t Summary key points --  |g 11.7.  |t Further reading --  |g 11.8.  |t Exercises --  |t References --  |g 12.1.  |t Introduction --  |g 12.2.  |t Expected value of perfect information --  |g 12.3.  |t Expected value of partial perfect information --  |g 12.3.1.  |t Computation --  |g 12.3.2.  |t Notes on EVPPI --  |g 12.4.  |t Expected value of sample information --  |g 12.4.1.  |t Computation --  |g 12.5.  |t Expected net benefit of sampling --  |g 12.6.  |t Summary key points --  |g 12.7.  |t Further reading --  |g 12.8.  |t Exercises --  |t References --  |g A2.1.  |t Normal distribution --  |g A2.2.  |t Binomial distribution --  |g A2.3.  |t Multinomial distribution --  |g A2.4.  |t Uniform distribution --  |g A2.5.  |t Exponential distribution --  |g A2.6.  |t Gamma distribution --  |g A2.7.  |t Beta distribution --  |g A2.8.  |t Dirichlet distribution. 
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