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|b Wiley InterScience
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|a Evidence synthesis for decision making in healthcare /
|c Nicky J. Welton [and others].
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|a Chichester, West Sussex :
|b Wiley,
|c 2012.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a Statistics in practice
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|a Includes bibliographical references and index.
|
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|6 880-01
|a Introduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design.
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|a Print version record and CIP data provided by publisher.
|
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|a In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixe.
|
590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Health services administration.
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650 |
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|a Evidence-based medicine.
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|a Bayesian statistical decision theory.
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|a Decision making
|x Mathematical models.
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|
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|a Statistics.
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|a Decision Support Techniques
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|a Statistics as Topic
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|a Evidence-Based Medicine
|x economics
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|a Models, Statistical
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|a Patient Care Management
|x methods
|
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|a Patient Care Management
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|a Health Services Administration
|
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|a Evidence-Based Medicine
|
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|
2 |
|a Evidence-Based Practice
|
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|
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|a Services de santé
|x Administration.
|
650 |
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|a Médecine factuelle.
|
650 |
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|a Théorie de la décision bayésienne.
|
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|a Prise de décision
|x Modèles mathématiques.
|
650 |
|
6 |
|a Statistiques.
|
650 |
|
6 |
|a Statistique.
|
650 |
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7 |
|a statistics.
|2 aat
|
650 |
|
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|a MEDICAL
|x Administration.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Practice Management & Reimbursement.
|2 bisacsh
|
650 |
|
7 |
|a Statistics
|2 fast
|
650 |
|
7 |
|a Decision making
|x Mathematical models
|2 fast
|
650 |
|
7 |
|a Bayesian statistical decision theory
|2 fast
|
650 |
|
7 |
|a Evidence-based medicine
|2 fast
|
650 |
|
7 |
|a Health services administration
|2 fast
|
655 |
|
4 |
|a Internet Resources.
|
700 |
1 |
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|a Welton, Nicky J.
|
758 |
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|i has work:
|a Evidence synthesis for decision making in healthcare (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCG3hPVYrycKpkv4ctyhtBq
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
8 |
|i Print version:
|t Evidence synthesis for decision making in healthcare.
|d Chichester, West Sussex : John Wiley & Sons, 2012
|z 9780470061091
|w (DLC) 2011051684
|
830 |
|
0 |
|a Statistics in practice.
|
856 |
4 |
0 |
|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=881533
|z Texto completo
|
880 |
0 |
0 |
|6 505-01/(S
|g Machine generated contents note:
|g 1.1.
|t rise of health economics --
|g 1.2.
|t Decision making under uncertainty --
|g 1.2.1.
|t Deterministic models --
|g 1.2.2.
|t Probabilistic decision modelling --
|g 1.3.
|t Evidence-based medicine --
|g 1.4.
|t Bayesian statistics --
|g 1.5.
|t NICE --
|g 1.6.
|t Structure of the book --
|g 1.7.
|t Summary key points --
|g 1.8.
|t Further reading --
|t References --
|g 2.1.
|t Introduction to Bayesian methods --
|g 2.1.1.
|t What is a Bayesian approach--
|g 2.1.2.
|t Likelihood --
|g 2.1.3.
|t Bayes' theorem and Bayesian updating --
|g 2.1.4.
|t Prior distributions --
|g 2.1.5.
|t Summarising the posterior distribution --
|g 2.1.6.
|t Prediction --
|g 2.1.7.
|t More realistic and complex models --
|g 2.1.8.
|t MCMC and Gibbs sampling --
|g 2.2.
|t Introduction to WinBUGS --
|g 2.2.1.
|t BUGS language --
|g 2.2.2.
|t Graphical representation --
|g 2.2.3.
|t Running WinBUGS --
|g 2.2.4.
|t Assessing convergence in WinBUGS --
|g 2.2.5.
|t Statistical inference in WinBUGS --
|g 2.2.6.
|t Practical aspects of using WinBUGS --
|g 2.3.
|t Advantages and disadvantages of a Bayesian approach --
|g 2.4.
|t Summary key points --
|g 2.5.
|t Further reading --
|g 2.6.
|t Exercises --
|t References --
|g 3.1.
|t Introduction --
|g 3.2.
|t Decision tree models --
|g 3.3.
|t Model parameters --
|g 3.3.1.
|t Effects of interventions --
|g 3.3.2.
|t Quantities relating to the clinical epidemiology of the clinical condition being treated --
|g 3.3.3.
|t Utilities --
|g 3.3.4.
|t Resource use and costs --
|g 3.4.
|t Deterministic decision tree --
|g 3.5.
|t Stochastic decision tree --
|g 3.5.1.
|t Presenting the results of stochastic economic decision models --
|g 3.6.
|t Sources of evidence --
|g 3.7.
|t Principles of synthesis for decision models (motivation for the rest of the book) --
|g 3.8.
|t Summary key points --
|g 3.9.
|t Further reading --
|g 3.10.
|t Exercises --
|t References --
|g 4.1.
|t Introduction --
|g 4.2.
|t Fixed Effect model --
|g 4.3.
|t Random Effects model --
|g 4.3.1.
|t predictive distribution --
|g 4.3.2.
|t Prior specification for τ --
|g 4.3.3.
|t 'Exact' Random Effects model for Odds Ratios based on a Binomial likelihood --
|g 4.3.4.
|t Shrunken study level estimates --
|g 4.4.
|t Publication bias --
|g 4.5.
|t Study validity --
|g 4.6.
|t Summary key points --
|g 4.7.
|t Further reading --
|g 4.8.
|t Exercises --
|t References --
|g 5.1.
|t Introduction --
|g 5.2.
|t Random effects meta-regression models --
|g 5.2.1.
|t Generic random effect meta-regression model --
|g 5.2.2.
|t Random effects meta-regression model for Odds Ratio (OR) outcomes using a Binomial likelihood --
|g 5.2.3.
|t Autocorrelation and centring covariates --
|g 5.3.
|t Limitations of meta-regression --
|g 5.4.
|t Baseline risk --
|g 5.4.1.
|t Model for including baseline risk in a meta-regression on the (log) OR scale --
|g 5.4.2.
|t Final comments on including baseline risk as a covariate --
|g 5.5.
|t Summary key points --
|g 5.6.
|t Further reading --
|g 5.7.
|t Exercises --
|t References --
|g 6.1.
|t Introduction --
|g 6.2.
|t Random Effects model revisited --
|g 6.3.
|t Assessing model fit --
|g 6.3.1.
|t Deviance --
|g 6.3.2.
|t Residual deviance --
|g 6.4.
|t Model comparison --
|g 6.4.1.
|t Effective number of parameters, pD --
|g 6.4.2.
|t Deviance Information Criteria --
|g 6.5.
|t Exploring inconsistency --
|g 6.5.1.
|t Cross-validation --
|g 6.5.2.
|t Mixed predictive checks --
|g 6.6.
|t Summary key points --
|g 6.7.
|t Further reading --
|g 6.8.
|t Exercises --
|t References --
|g 7.1.
|t Introduction --
|g 7.2.
|t Evaluation of decision models: One-stage vs two-stage approach --
|g 7.3.
|t Sensitivity analyses (of model inputs and model specifications) --
|g 7.4.
|t Summary key points --
|g 7.5.
|t Further reading --
|g 7.6.
|t Exercises --
|t References --
|g 8.1.
|t Introduction --
|g 8.2.
|t Prior and posterior simulation in a probabilistic model: Maple Syrup Urine Disease (MSUD) --
|g 8.3.
|t model for prenatal HIV testing --
|g 8.4.
|t Model criticism in multi-parameter models --
|g 8.5.
|t Evidence-based policy --
|g 8.6.
|t Summary key points --
|g 8.7.
|t Further reading --
|g 8.8.
|t Exercises --
|t References --
|g 9.1.
|t Why go beyond 'direct' head-to-head trials--
|g 9.2.
|t fixed treatment effects model for MTC --
|g 9.2.1.
|t Absolute treatment effects --
|g 9.2.2.
|t Relative treatment efficacy and ranking --
|g 9.3.
|t Random Effects MTC models --
|g 9.4.
|t Model choice and consistency of MTC evidence --
|g 9.4.1.
|t Techniques for presenting and understanding the results of MTC --
|g 9.5.
|t Multi-arm trials --
|g 9.6.
|t Assumptions made in mixed treatment comparisons --
|g 9.7.
|t Embedding an MTC within a cost-effectiveness analysis --
|g 9.8.
|t Extension to continuous, rate and other outcomes --
|g 9.9.
|t Summary key points --
|g 9.10.
|t Further reading --
|g 9.11.
|t Exercises --
|t References --
|g 10.1.
|t Introduction --
|g 10.2.
|t Continuous and discrete time Markov models --
|g 10.3.
|t Decision analysis with Markov models --
|g 10.3.1.
|t Evaluating Markov models --
|g 10.4.
|t Estimating transition parameters from a single study --
|g 10.4.1.
|t Likelihood --
|g 10.4.2.
|t Priors and posteriors for multinomial probabilities --
|g 10.5.
|t Propagating uncertainty in Markov parameters into a decision model --
|g 10.6.
|t Estimating transition parameters from a synthesis of several studies --
|g 10.6.1.
|t Challenges for meta-analysis of evidence on Markov transition parameters --
|g 10.6.2.
|t relationship between probabilities and rates --
|g 10.6.3.
|t Modelling study effects --
|g 10.6.4.
|t Synthesis of studies reporting aggregate data --
|g 10.6.5.
|t Incorporating studies that provide event history data --
|g 10.6.6.
|t Reporting results from a Random Effects model --
|g 10.6.7.
|t Incorporating treatment effects --
|g 10.7.
|t Summary key points --
|g 10.8.
|t Further reading --
|g 10.9.
|t Exercises --
|t References --
|g 11.1.
|t Introduction --
|g 11.2.
|t Deriving a prior distribution from observational evidence --
|g 11.3.
|t Bias allowance model for the observational data --
|g 11.4.
|t Hierarchical models for evidence from different study designs --
|g 11.5.
|t Discussion --
|g 11.6.
|t Summary key points --
|g 11.7.
|t Further reading --
|g 11.8.
|t Exercises --
|t References --
|g 12.1.
|t Introduction --
|g 12.2.
|t Expected value of perfect information --
|g 12.3.
|t Expected value of partial perfect information --
|g 12.3.1.
|t Computation --
|g 12.3.2.
|t Notes on EVPPI --
|g 12.4.
|t Expected value of sample information --
|g 12.4.1.
|t Computation --
|g 12.5.
|t Expected net benefit of sampling --
|g 12.6.
|t Summary key points --
|g 12.7.
|t Further reading --
|g 12.8.
|t Exercises --
|t References --
|g A2.1.
|t Normal distribution --
|g A2.2.
|t Binomial distribution --
|g A2.3.
|t Multinomial distribution --
|g A2.4.
|t Uniform distribution --
|g A2.5.
|t Exponential distribution --
|g A2.6.
|t Gamma distribution --
|g A2.7.
|t Beta distribution --
|g A2.8.
|t Dirichlet distribution.
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