Molecular diagnostics : the key driver in personalized cancer medicine /

Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Jørgensen, Jan Trøst, Winther, Henrik
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Pan Stanford Pub., ©2010.
Temas:
Molecular diagnosis.
Genetic screening.
Biochemical markers.
Neoplasms > diagnosis
Biomarkers
Genomics > methods
Molecular Diagnostic Techniques
Genetic Testing
Diagnostics moléculaires.
Dépistage génétique.
Marqueurs biologiques.
MEDICAL > Oncology.
MEDICAL > Pathology.
MEDICAL > Pharmacy.
Biochemical markers
Genetic screening
Molecular diagnosis
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction / Jan Trs?t Jr?gensen and Henrik Winther
  • Developing molecular diagnostics in cancer / Henrik Winther and Jan Trs?t Jr?gensen
  • The estrogen and progesterone receptors : setting the scene for pharmacodiagnostics / Kwok-Leung Cheung
  • The development of the HercepTest : from bench to bedside / Jan Trs?t Jr?gensen and Henrik Winther
  • Predictive biomarkers and translational cancer medicine / Anne-Sofie Schrohl [and others]
  • Pharmacodiagnostic testing : immunohistology / Anthony S.-Y. Leong and Trishe Y.-M. Leong
  • In situ hybridisation for pharmacodiagnostic testing / John M.S. Bartlett and Fiona M. Campbell
  • MammaPrint translating research into a diagnostic test / Annuska M. Glas, Leonie Delahaye and Oscar Krijgsman
  • DNA biomarkers in the diagnosis and management of cancer / Reza Rafiolsadat Serizawa and Per Guldberg
  • Validating the analytical power and parameters of an immunohistochemical test / Sr?en Nielsen
  • Drug and pharmacodiagnostic co-development : statistical considerations / Richard Simon
  • Clinical validation of biomarkers in cancer / Sumithra J. Mandrekar and Daniel J. Sargent
  • Pharmacogenomic markers for cancer therapy / Sharon Marsh
  • Safety and effective biomakers in oncology : a regulatory drug and device perspective / Atiqur Rahman and Francis Kalush
  • Personalizing treatment selection for breast cancer / Lajos Pusztai and Chit Cheng Yeoh
  • Pharmacodiagnostics and personalized medicine in cancer / Jan Trs?t Jr?gensen.

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