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Molecular diagnostics : the key driver in personalized cancer medicine /

Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Jørgensen, Jan Trøst, Winther, Henrik
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Pan Stanford Pub., ©2010.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Molecular diagnostics :  |b the key driver in personalized cancer medicine /  |c editors, Jan Trost Jorgensen, Henrik Winther. 
260 |a Singapore :  |b Pan Stanford Pub.,  |c ©2010. 
300 |a 1 online resource (x, 351 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
520 |a Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked to therapy. 
588 0 |a Print version record. 
505 0 |a Introduction / Jan Trs?t Jr?gensen and Henrik Winther -- Developing molecular diagnostics in cancer / Henrik Winther and Jan Trs?t Jr?gensen -- The estrogen and progesterone receptors : setting the scene for pharmacodiagnostics / Kwok-Leung Cheung -- The development of the HercepTest : from bench to bedside / Jan Trs?t Jr?gensen and Henrik Winther -- Predictive biomarkers and translational cancer medicine / Anne-Sofie Schrohl [and others] -- Pharmacodiagnostic testing : immunohistology / Anthony S.-Y. Leong and Trishe Y.-M. Leong -- In situ hybridisation for pharmacodiagnostic testing / John M.S. Bartlett and Fiona M. Campbell -- MammaPrint translating research into a diagnostic test / Annuska M. Glas, Leonie Delahaye and Oscar Krijgsman -- DNA biomarkers in the diagnosis and management of cancer / Reza Rafiolsadat Serizawa and Per Guldberg -- Validating the analytical power and parameters of an immunohistochemical test / Sr?en Nielsen -- Drug and pharmacodiagnostic co-development : statistical considerations / Richard Simon -- Clinical validation of biomarkers in cancer / Sumithra J. Mandrekar and Daniel J. Sargent -- Pharmacogenomic markers for cancer therapy / Sharon Marsh -- Safety and effective biomakers in oncology : a regulatory drug and device perspective / Atiqur Rahman and Francis Kalush -- Personalizing treatment selection for breast cancer / Lajos Pusztai and Chit Cheng Yeoh -- Pharmacodiagnostics and personalized medicine in cancer / Jan Trs?t Jr?gensen. 
545 0 |a Dr Jan Trost Jorgensen holds an MSc degree in pharmacy and a PhD in clinical pharmacy from the Faculty of Pharmaceutical Sciences, University of Copenhagen. He has worked with drug development in biotech and pharmaceutical companies for more than 25 years, and within the last 10 years his focus has been on drug-diagnostic co-development projects within cancer. Dr Jorgensen is a strong supporter of more individualized pharmacotherapy and has published a number of scientific papers on oncology as well as on stratified and personalized medicine. 
546 |a English. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Molecular diagnosis. 
650 0 |a Genetic screening. 
650 0 |a Biochemical markers. 
650 2 |a Neoplasms  |x diagnosis 
650 2 2 |a Biomarkers 
650 2 2 |a Genomics  |x methods 
650 2 2 |a Molecular Diagnostic Techniques 
650 2 |a Genetic Testing 
650 6 |a Diagnostics moléculaires. 
650 6 |a Dépistage génétique. 
650 6 |a Marqueurs biologiques. 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
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650 7 |a Biochemical markers  |2 fast 
650 7 |a Genetic screening  |2 fast 
650 7 |a Molecular diagnosis  |2 fast 
700 1 |a Jørgensen, Jan Trøst. 
700 1 |a Winther, Henrik. 
758 |i has work:  |a Molecular diagnostics (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGCfW87xH69V7PMRcbwbJP  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t Molecular diagnostics.  |d Singapore : Stanford Pub., ©2010  |z 9789814241441  |z 981424144X  |w (OCoLC)648093414 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=495936  |z Texto completo 
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