Life Science Automation Fundamentals and Applications.
Gain thorough understanding of the science and engineering behind todays most advanced life sciences automation devices, systems, and technologies and their applications in biotechnology, pharmacology, and healthcare with this cutting-edge book. This comprehensive interdisciplinary resource details...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Norwood :
Artech House,
2007.
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Colección: | Artech House bioinformatics & biomedical imaging series.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Life Science Automation Fundamentals and Applications; Contents v ; Preface xv; Part I Life Science Basis for Automation 1; Chapter 1 Introduction to Nucleic Acids and ClinicalLaboratory Testing 3; 1.1 Basics of Nucleic Acid Structure 4; 1.1.1 General Principles 4; 1.1.2 In Vitro Aspects of DNA 5; 1.1.3 Unidirectional Flow of Genetic Information: The Central Dogma 9; 1.2 Manipulation of DNA Under Testing Conditions 10; 1.2.1 Extraction 10; 1.2.2 Amplification 10; 1.2.3 Detection 13; 1.3 Statistics and Test Utilization Used in Medical Decision Making 16; 1.3.1 Sensitivity and Specificity 17.
- 1.3.2 Predictive Values 181.3.3 Preanalytical Versus Analytical Stages of Testing 19; 1.4 Summary 20; Reference 21; Chapter 2 Basic Analytical Chemistry for Engineers 23; 2.1 Introduction 23; 2.2 Chromatographic Separation Methods 24; 2.2.1 General Principles 24; 2.2.2 Gas Chromatographic Methods 25; 2.2.3 Liquid Chromatographic Methods 26; 2.2.4 Electrophoresis 27; 2.3 Bioanalytical Detection Methods 30; 2.3.1 Protein Anal 30; 2.3.2 DNA and RNA Analysis 36; 2.3.3 Enzymatic Analysis 40; 2.3.4 Immunological Methods 49; 2.4 Physical Detection Methods 52; 2.4.1 Atomic Spectroscopy 53.
- 2.4.2 Optical Molecule Spectroscopy 542.4.3 Nuclear Magnetic Resonance Spectroscopy 58; 2.4.4 Mass Spectrometry 59; 2.5 Future Challenges 63; References 63; Chapter 3 Basic Health Care Delivery for Engineers 67; 3.1 Introduction 67; 3.2 The Health Care System: A Holistic Perspective 68; 3.2.1 The Department of Veterans Affairs 70; 3.2.2 The Military Health Services System 70; 3.2.3 Indian Health Service 71; 3.2.4 Public Health Service 72; 3.3 Health Care Subsystems 72; 3.4 Evidence-Based Decision Making in Health Care Delivery 74; 3.4.1 The Structure of Clinical Decision Making 75.
- 3.4.2 Automation Applied to Types of Clinical Decision Making 763.4.3 Automation Applied to the Clinical Decision Process 78; 3.5 Care Providers 80; 3.5.1 Health Professionals 80; 3.5.2 Organizational Providers 81; 3.5.3 Automated Devices: Control and Oversight 83; 3.5.4 Value Migration in the Health System 84; 3.6 The Mandate for Improved Clinical Outcomes 86; 3.7 The Support Function of the Health System 88; 3.7.1 Financing the Health Care System 88; 3.7.2 Development and Diffusion of Medical Technology 92; 3.8 Conclusions 95; References 95.
- Part II Engineering Basis for Life Science AutomationChapter 4 Principles of Human-Machine Interfacesand Interactions 101; 4.1 Introduction 101; 4.2 Fundamentals of Human-Machine Interaction 102; 4.2.1 Robotics and Machines for Life Science Automation 103; 4.2.2 Design of Automation Systems 103; 4.2.3 Performance of Human-Machine Systems 106; 4.2.4 Human-Machine Teaming 108; 4.2.5 Communication 109; 4.3 Current Research 110; 4.3.1 HMI Interaction Via Haptic Devices 110; 4.3.2 Teamwork 112; 4.3.3 Robots for Performance 113; 4.4 Future Issues 115.