Applications of toxicogenomic technologies to predictive toxicology and risk assessment /

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The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identif...

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Détails bibliographiques
Cote:Libro Electrónico
Collectivité auteur: National Research Council (U.S.). Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology
Format: Électronique eBook
Langue:Inglés
Publié: Washington, D.C. : National Academies Press, ©2007.
Sujets:
Genetic toxicology.
DNA microarrays > Statistical methods.
Health risk assessment.
Carcinogenesis.
Risk assessment.
Toxicogenetics > methods
Health Status Indicators
Oligonucleotide Array Sequence Analysis
Hazardous Substances > toxicity
Risk Assessment
Models, Statistical
Carcinogenesis
Risques pour la santé > Évaluation.
Cancérogenèse.
Toxicologie génétique.
Puces à ADN > Méthodes statistiques.
Évaluation du risque.
risk assessment.
HEALTH & FITNESS > Diseases > Genetic.
MEDICAL > Genetics.
Risk assessment
DNA microarrays > Statistical methods
Genetic toxicology
Health risk assessment
Accès en ligne:Texto completo
Table des matières:
  • Introduction
  • Toxicogenomic technologies
  • Experimental design and data analysis
  • Application to exposure assessment
  • Application to hazard screening
  • Application to analyzing variation in human susceptibility
  • Application to the study of mechanisms of action
  • Other potential applications of toxicogenomic technologies to risk assessment
  • Validation
  • Sample and data collection and analysis
  • Ethical, legal, and social issues
  • Conculsions and recommendations.

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