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Facilitative glucose transporters in articular chondrocytes : expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines /
Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchyma...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Berlin :
Springer Verlag,
2008.
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| Colección: | Advances in anatomy, embryology, and cell biology ;
200. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans. |
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| Descripción Física: | 1 online resource (vi, 88 pages) : illustrations |
| Bibliografía: | Includes bibliographical references (pages 69-84) and index. |
| ISBN: | 9783540788997 3540788999 3540788980 9783540788980 |