The immune synapse as a novel target for therapy /

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The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell-APC junction. It plays an essential role in the control and nature...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Graca, Luis, MD
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel ; Boston : [London] : Birkhäuser ; [Springer, distributor], ©2008.
Colección:PIR (Series)
Temas:
Synapses.
Immune response > Molecular aspects.
Immune response > Regulation.
Antigen Presentation > physiology
Immunological Synapses > physiology
T-Lymphocytes > physiology
Synapses
Réaction immunitaire > Aspect moléculaire.
Réaction immunitaire > Régulation.
MEDICAL > Immunology.
T-Lymphocytes > physiology.
Lymphocyte Activation.
Antigens, CD > physiology.
Antigen Presentation.
Immune Tolerance.
Biomédecine.
Sciences de la vie.
Immune response > Molecular aspects
Immune response > Regulation
Acceso en línea:Texto completo
Descripción
Sumario:The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell-APC junction. It plays an essential role in the control and nature of the immune response. In recent years several approaches have been developed to reprogramming the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as the ones targeting the lymphocyte co-receptor, co-stimulatory and adhesion molecules (CD3, CD4, CD.
Descripción Física:1 online resource (xi, 192 pages) : illustrations
Bibliografía:Includes bibliographical references and index.
ISBN:9783764382964
3764382961
9783764382957
3764382953
9786611140915
6611140913

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